280744-73-2

Upstream product

• 95-75-0 3,4-Dichlorotoluene 
• 280744-30-1 4,5-dichloro-2-(4-nitrobenzoyl)benzaldehyde acylal 
• 280744-28-7 3,4-dichloro-2-(4-nitrobenzoyl)toluene 
• 122-04-3 4-nitro-benzoyl chloride 
• 280744-55-0 6,7-dichloro-1-(4-nitrophenyl)phthalazine 

Downstream Products

• 280744-37-8 1-(4-acetaminophenyl)-6,7-dichlorophthalazine 
• 280744-39-0 4-(4-acetaminophenyl)-6,7-dichloro-1-methyl-1,2-dihydrophthalazine 
• 280744-41-4 4-(4-acetaminophenyl)-6,7-dichloro-1-methyl-2-phenyloxycarbonyl-1,2-dihydrophthalazine 
• 280744-44-7 4-(4-acetaminophenyl)-2-(N-cyclopropylcarbamoyl)-6,7-dichloro-1-methyl-1,2-dihydrophthalazine 
• 280744-43-6 4-(4-acetaminophenyl)-2-(N-butylcarbamoyl)-6,7-dichloro-1-methyl-1,2-dihydrophthalazine 
• 501107-01-3 4-(4-acetaminophenyl)-6,7-dichloro-1-methyl-2-(pyrrolidine-1-carbonyl)-1,2-dihydrophthalazine 

Relevant academic research and scientific papers

Synthesis of new 1,2-dihydrophthalazines

New 6-chloro- and 6,7-dichloro-4-(4-aminophenyl)-2-(N-alkylcarbamoyl)-1,2-dihydrophthalazines (12, 18) were synthesized starting from 6-chloro- and 6,7-dichloro-4-(4-nitrophenyl)phthalazine (8). Routes to 1-unsubstituted (12) and 1-methyl (18) derivatives are different. Key intermediates 8 were prepared from 4-chloro- and 3,4-dichlorotoluene via ortho-formylbenzophenone derivatives 7.