280762-60-9Relevant academic research and scientific papers
Versatile synthesis of (+)-deoxypyridinoline, a biochemical marker for diagnosis of osteoporosis
Adamczyk, Maciej,Rao Akireddy, Srinivasa,Reddy, Rajarathnam E.
, p. 3107 - 3110 (2007/10/03)
A versatile chiral synthesis of the bone collagen cross-link, (+)-deoxypyridinoline (Dpd, 1) was described starting from a 3-hydroxypyridine derivative (2) via sequential introduction of three amino acid chains followed by hydrolysis. The key synthon 2, was prepared from vitamin B6 (6).
