280763-60-2Relevant academic research and scientific papers
A Silver-Catalyzed Modular Intermolecular Access to 6,6-Spiroketals
Ahrens, Alexander,Heinrich, Niklas F.,Kohl, Simon R.,Hokamp, Martha,Rudolph, Matthias,Rominger, Frank,Hashmi, A. Stephen K.
, p. 5605 - 5615 (2019/12/11)
A modular synthesis of 6,6-spiroketals via silver catalysis is reported. By combining an intermolecular Michael addition and a 6-endo-dig cyclization, this cascade reaction allows the modular preparation of highly substituted 6,6-spiroketals by combining two substrate molecules. Established methods accessing this interesting substructure are complemented by this new transformation. The protocol tolerates diverse substitution patterns and functional groups. (Figure presented.).
Metal/Benzoyl Peroxide (BPO)-Controlled Chemoselective Cycloisomerization of (o-Alkynyl)phenyl Enaminones: Synthesis of α-Naphthylamines and Indeno[1,2-c]pyrrolones
Zhang, Fangfang,Qin, Zhengchen,Kong, Lingkai,Zhao, Yulei,Liu, Yuanyuan,Li, Yanzhong
, p. 5150 - 5153 (2016/10/14)
Synthetic methods involving chemoselective tandem reactions for the synthesis of α-naphthylamines and indeno[1,2-c]pyrrolones starting from (o-aklynyl)phenyl enaminones are described. When reactions were carried out in N,N-dimethylformamide (DMF) using a AgNO3 catalyst, α-naphthylamines were obtained in up to 89% isolated yields within 2 h. Whereas indeno[1,2-c]pyrrolones were produced in high isolated yields in the presence of benzoyl peroxide (BPO) and CuCl catalysis.
A new rearrangement of cyclic allenes via 1,2-dehydro[10]annulenes: Formation of benzo[c]fluorenones
Rodríguez, David,Navarro-Vázquez, Armando,Castedo, Luis,Domínguez, Domingo,Saá, Carlos
, p. 2717 - 2720 (2007/10/03)
A new rearrangement of cyclic allenes giving benzo[c]fluorenones was observed when studying intramolecular dehydro Diels-Alder reactions of silyl-substituted alkynes with arenynes (aryldiacetylenes).
Intramolecular [4 + 2] Cycloaddition Reactions of Diarylacetylenes: Synthesis of Benzo[b]fluorene Derivatives via Cyclic Allenes
Rodríguez, David,Navarro, Armando,Castedo, Luis,Domínguez, Domingo,Saá, Carlos
, p. 1497 - 1500 (2007/10/03)
(Equation Presented) 2-Propynyldiarylacetylenes undergo thermal intramolecular [4 + 2] cycloaddition to give benzo[b]fluorene derivatives in good yields. The hybridization of the tether connecting the reacting alkynes has a pronounced effect on the course
