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2-amino-4-{2-[5-(N,N'-bis((R)-1-ethoxycarbonyl-2-benzylthio)-ethyl)phosphonamido]furanyl}-5-isobutylthiazole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

280783-04-2

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280783-04-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 280783-04-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,0,7,8 and 3 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 280783-04:
(8*2)+(7*8)+(6*0)+(5*7)+(4*8)+(3*3)+(2*0)+(1*4)=152
152 % 10 = 2
So 280783-04-2 is a valid CAS Registry Number.

280783-04-2Downstream Products

280783-04-2Relevant academic research and scientific papers

Discovery of phosphonic diamide prodrugs and their use for the oral delivery of a series of fructose 1,6-bisphosphatase inhibitors

Dang, Qun,Kasibhatla, Srinivas Rao,Jiang, Tao,Fan, Kevin,Liu, Yan,Taplin, Frank,Schulz, William,Cashion, Daniel K.,Reddy, K. Raja,Van Poelje, Paul D.,Fujitaki, James M.,Potter, Scott C.,Erion, Mark D.

experimental part, p. 4331 - 4339 (2009/05/30)

Like most phosphonic acids, the recently discovered potent and selective thiazole phosphonic acid inhibitors of fructose 1,6-bisphosphatase (FBPase) exhibited low oral bioavailability (OBAV) and therefore required a prodrug to achieve oral efficacy. Synth

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