28093-86-9

Basic information

• Product Name: 2,5-Cyclohexadien-1-one, 4-methoxy-4-phenyl-
• CAS NO: 28093-86-9
• Molecular Formula: C13H12O2
• Molecular Weight: 200.237
• Mol File: 28093-86-9.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 2,5-Cyclohexadien-1-one, 4-methoxy-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Cyclohexadien-1-one, 4-methoxy-4-phenyl-(28093-86-9)
• EPA Substance Registry System: 2,5-Cyclohexadien-1-one, 4-methoxy-4-phenyl-(28093-86-9)

Safety Data

• Hazardous Substances Data: 28093-86-9(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 92-69-3 4-Phenylphenol 
• 4075-79-0 4-phenylacetanilide 
• 146474-20-6 N-Benzoyl-4-methoxy-4-phenyl-p-benzoquinol imine 
• 146474-21-7 4-Methoxy-4-phenyl-2,5-cyclohexadienone N-acetylimine 
• 103594-20-3 8-Methoxy-8-phenyl-1,4-dioxa-spiro[4.5]deca-6,9-diene 
• 103594-13-4 (1,4,4-Trimethoxy-cyclohexa-2,5-dienyl)-benzene 
• 92-67-1 4-phenylalanine 

Downstream Products

• 122698-76-4 4-methoxy-4-phenyl-5-(2-propenyl)-2-cyclohexenone 
• 122698-75-3 4,5-diphenyl-4-methoxy-2-cyclohexenone 
• 92-04-6 2-chloro-4-phenylphenol 
• 1431660-76-2 3,5-diphenyl-1H-indole 
• 1312922-16-9 3-(4-methoxybiphenyl-2-yl)-1H-indole 
• 92-69-3 4-Phenylphenol 
• 122698-78-6 5-(2-(trimethylsilyl)ethynyl)-4-phenyl-4-methoxycyclohex-2-en-1-one 
• 122698-77-5 5-(1,3-dithian-2-yl)-4-methoxy-4-phenylcyclohex-2-en-1-one 

Relevant articles and documents

Copper-Catalyzed Chemo- and Diastereoselective 1,3-Dipolar Cycloaddition of Carbonyl Ylide and Aldehyde-Tethered-Cyclohexadienone to Access Polycyclic Systems

A copper-catalyzed tandem intermolecular ylide formation/intramolecular cycloaddition of diazo compounds and aldehyde-tethered-cyclohexadienones was reported, chemo- and diastereoselectively providing oxapolycyclic frameworks in moderate to excellent yields under mild conditions. This reaction creates two C?C bonds and one C?O bond with five stereocentres including two all-carbon quaternary centres. Moreover, the late-stage diversification of products can be realized via chemoselective substitutions. (Figure presented.).

Zinc-catalyzed regioselective C-P coupling of p-quinol ethers with secondary phosphine oxides to afford 2-phosphinylphenols

The zinc triflate-catalyzed highly regioselective C-P cross coupling reaction of p-quinol ethers with secondary phosphine oxides is reported. The reaction provides a facile alternative method for the synthesis of 2-phosphinylphenols in good to high yields. Mechanistically, zinc triflate may serve as an oxophilic σ-Lewis acid to activate the C-O bond in p-quinol ether first. Then the regioselective attack of the phosphorus nucleophile at the α-carbon position takes place to form the C-P bond and give the product. In addition, α-alkynyl substituted p-quinol ethers also react with secondary phosphine oxides in the same reaction mode to give 6-alkynyl 2-phosphinylphenols in the presence of the zinc catalyst.

Iodobenzene and m-chloroperbenzoic acid mediated oxidative dearomatization of phenols

Oxidative dearomatization of 2- and 4-substituted phenols to their corresponding benzoquinone monoketals by catalytic amount of iodobenzene, and m-CPBA as a co-oxidant has been achieved via in situ generation of PhIO2, a hypervalent iodine(V) s