2810-42-6

Basic information

• Product Name: Acetamide, N,N'-1,2-phenylenebis[2-chloro-
• CAS NO: 2810-42-6
• Molecular Formula: C10H10Cl2N2O2
• Molecular Weight: 261.108
• Mol File: 2810-42-6.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Acetamide, N,N'-1,2-phenylenebis[2-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N,N'-1,2-phenylenebis[2-chloro-(2810-42-6)
• EPA Substance Registry System: Acetamide, N,N'-1,2-phenylenebis[2-chloro-(2810-42-6)

Safety Data

• Hazardous Substances Data: 2810-42-6(Hazardous Substances Data)

Upstream product

• 79-04-9 chloroacetyl chloride 
• 95-54-5 1,2-diamino-benzene 
• 4015-58-1 monochloroacetic acid anhydride 

Downstream Products

• 112818-62-9 N,N'-(1,2-phenylene)bis(2-(piperidin-1-yl)acetamide) 
• 876336-74-2 N,N'-(1,2-phenylene)bis(2-(diethylamino)acetamide) 
• 100468-81-3 1,2-bis-(2-triethylammonio-acetylamino)-benzene; dichloride 
• 1196-57-2 quinoxalin-2⁽¹⁾-one 
• 139593-75-2 4-Phenyl-2,3,4,5,6,7-hexahydro-1H-1,4,7-benzotriazonin-2,5-dione 
• 1149390-75-9 H₂L⁴ 
• 630120-89-7 2-(4-pyridin-2-ylpiperazin-1-yl)-N-(2-{[(4-pyridin-2-ylpiperazin-1-yl)acetyl]amino}phenyl)acetamide 
• 332180-06-0 N,N'-bis(2-dimethylaminoethyl)-1,2-diaminobenzene 
• 511281-82-6 2-(2-amino-phenylsulfanyl)-N-{2-[2-(2-amino-phenylsulfanyl)-acetylamino]-phenyl}-acetamide 
• 642444-36-8 2-hexylamino-N-[2-(2-hexylamino-acetylamino)-phenyl]acetamide 

Relevant articles and documents

Metal-directed self-assembly of bimetallic dithiocarbamate transition metal cryptands and their binding capabilities

A novel family of redox-active dinuclear transition metal based cryptands self-assembled from dithiocarbamate ligands has been synthesised; depending upon the nature of the spacer groups these new cryptand systems have been shown to electrochemically reco

Ortho-phenylenediamine-based open and macrocyclic receptors in selective sensing of H2PO4-, ATP and ADP under different conditions

Ortho-phenylenediamine-based open and macrocyclic receptors have been designed and synthesized. The open receptor 1 and the macrocyclic receptor 2 fluorimetrically distinguish H2PO4- from the other anions examined in CH3CN with appreciable binding constant values. As practical applications, they are also sensible to nucleotides in aq. CH3CN (1:1, v/v). The receptor 1 shows significant emission change upon complexation of ATP and ADP. ADP is selectively distinguished by a ratiometric change in emission. In contrast, the macrocyclic receptor 2, under similar conditions, shows good binding with ATP over the others.

BIS(2-HALOACETAMIDO)-COMPOUNDS FOR USE AS LINKING AGENTS AND RESULTANT PRODUCTS WHICH COMPRISE ANTIBODIES, HALF-ANTIBODIES AND ANTIBODY FRAGMENTS

Bis(2-haloacetamido)- compounds for use as linkers to chemically cross-linking multiple thiol groups, and particularly, although not exclusively, the thiol groups of cysteine amino acids in peptide chains are described, along with their use as linking age

Synthesis, crystal analysis and DFT calculations of Ni(II) and Pd(II) complexes of 3,3'-((1,2-phenylenebis(azanediyl))bis(2-oxoethane-2,1-diyl))bis(1-allyl-1H-imidazole-3-ium)

Ni(II) and Pd(II) Complexes of 3,3'-((1,2-phenylenebis(azanediyl))bis(2-oxoethane-2,1-diyl))bis(1-allyl-1H-imidazole-3-ium) were synthesised in good yield and characterized by spectroscopic and X-ray diffraction techniques. These novel complexes, which are neutral in charge, possess square planar geometry where the coordination of the tetradentate ligand is through C2 of the imidazole moiety. These complexes are identified to be single cis-isomers as confirmed by 1H NMR and single crystal X-ray diffraction data. DFT/B3LYP calculations were also conducted using the theoretical model of the precursor heterocyclic ligand and Ni(II) and Pd(II) metal complexes. The results of these theoretical data which are calculated to be the structural parameters of optimized structures exhibited good agreement with those obtained from X-ray crystal diffraction analysis. Both metal complexes are subjected to further theoretical studies such as determination of the HOMO-LUMO gap, molecular electrostatic potential (MEP) and calculation of reactivity descriptors and the obtained results attest the superiority of these compounds as novel heterocyclic functional materials.

Bispidine dioxotetraaza macrocycles: A new class of bispidines for 64Cu PET imaging

The three new dioxo-tetraazamacrocyclic ligands with a fused, very rigid bispidine (3,7-diazabicyclo[3.3.1]nonane) group connecting the two tertiary amine donors, and ethyl, propyl, or benzene groups connecting the two amide donors are highly preorganized and lead to very stable, uncharged Cu II complexes. Solution spectroscopy and solid state structures indicate that these are square pyramidal with a solvent molecule occupying the apical position. Cyclic voltammetry defines a reversible CuIII/II couple and a strongly negative irreversible CuII/I couple (ca. -2 V vs Fc/Fc+), indicating that the CuII complexes are very stable in solution. This is supported by superoxide dismutase (SOD) and human serum challenge experiments as well as the biodistribution, which all show that the benzene-based ligand has the highest in vitro and in vivo stability and that this was expected on the basis of the macrocycle ring size and shape and the highest degree of preorganization. This ligand is easy to functionalize for a possible coupling to biological vector molecules and/or fluorescence markers for PET (positron emission tomography) and multimodal imaging (i.e., PET and optical imaging).