281214-26-4

Basic information

• Product Name: (R)-2-methylbutane-1,4-diyl bis(4-methylbenzenesulfonate)
• Synonyms: (R)-2-methylbutane-1,4-diyl bis(4-methylbenzenesulfonate)
• CAS NO: 281214-26-4
• Molecular Weight: 412.528
• Mol File: 281214-26-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-2-methylbutane-1,4-diyl bis(4-methylbenzenesulfonate)(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-methylbutane-1,4-diyl bis(4-methylbenzenesulfonate)(281214-26-4)
• EPA Substance Registry System: (R)-2-methylbutane-1,4-diyl bis(4-methylbenzenesulfonate)(281214-26-4)

Safety Data

• Hazardous Substances Data: 281214-26-4(Hazardous Substances Data)

Upstream product

• 73407-97-3 (2R,4E)-2-methyl-5-phenyl-4-penten-1-ol 
• 256508-91-5 (-)-(1R,2S,6S,7S)-N-[(2'R)-2'-methyl-3'-ethoxycarbonylpropionyl]-3,4-thiazatricyclo[5.2.1.0^2,6]deca-8-ene-3,3-dioxide 
• 369365-14-0 dimethyl (2S,3R)-3-methyl-2-O-tosylmalate 
• 369365-15-1 dimethyl (2R,3R)-2-methyl-3-phenylsultanylsuccinate 
• 369365-18-4 dimethyl (2RS,3R)-2-chloro-3-methylsuccinate 
• 50460-80-5 (2S)-2-Hydroxy-3-methyl-bernsteinsaeuredimethylester 
• 22644-27-5 (R)-methylsuccinic acid dimethyl ester 
• 2938-98-9 (R)-2-methylbutane-1,4-diol 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

Direct regiospecific and highly enantioselective intermolecular α-allylic alkylation of aldehydes by a combination of transition-metal and chiral amine catalysts

The first direct intermolecular regiospecific and highly enantioselective α-allylic alkylation of linear aldehydes by a combination of achiral bench-stable Pd0 complexes and simple chiral amines as co-catalysts is disclosed. The co-catalytic asymmetric chemoselective and regiospecific α-allylic alkylation reaction is linked in tandem with in situ reduction to give the corresponding 2-alkyl alcohols with high enantiomeric ratios (up to 98:2 e.r.; e.r.=enantiomeric ratio). It is also an expeditious entry to valuable 2-alkyl substituted hemiacetals, 2-alkyl-butane-1,4-diols, and amines. The concise co-catalytic asymmetric total syntheses of biologically active natural products (e.g., Arundic acid) are disclosed. Go organic! Direct intermolecular regiospecific and highly enantioselective α-allylic alkylation of linear aldehydes by a combination of achiral bench-stable Pd0 complexes and simple chiral amines as co-catalysts is disclosed (see scheme). Copyright

Asymmetric synthesis of 1,3- and 1,3,4-substituted pyrrolidines

Diastereoselective alkylation of N-acylnorbornene sultams 2 afforded a variety of enantiomerically pure products 3a-3e. Reduction with LiAlH4 (LAH) followed by ditosylation furnished chiral 1,4-ditosylates 5a-5e which underwent a cyclization reaction with primary amines to afford chiral 1,3- and 1,3,4-substituted pyrrolidines. (C) 2000 Elsevier Science Ltd.