50460-80-5

Basic information

• Product Name: dimethyl 2-hydroxy-3-methylbutanedioate
• Synonyms: dimethyl 2-hydroxy-3-methylbutanedioate
• CAS NO: 50460-80-5
• Molecular Weight: 176.169
• Mol File: 50460-80-5.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: dimethyl 2-hydroxy-3-methylbutanedioate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2-hydroxy-3-methylbutanedioate(50460-80-5)
• EPA Substance Registry System: dimethyl 2-hydroxy-3-methylbutanedioate(50460-80-5)

Safety Data

• Hazardous Substances Data: 50460-80-5(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 11003-23-9 Elaiophylin 
• 420-04-2 CYANAMID 
• 13398-41-9 (2S, 3S)-threo-β-methylmalic acid 
• 93504-92-8 2-hydroxy-3-methylbutanedioic acid diethyl ester 
• 63921-06-2 3-methyl-2-oxo-butane-1,4-dioic acid dimethyl ester 
• 108735-94-0 1-Ethyl 4-methyl 2-hydroxy 3-methylenebutanedioate 
• 608-41-3 erythro-2-hydroxy-3-methylbutane-1,4-dioic acid 
• 617-55-0 dimethyl (S)-malate 
• 74-88-4 methyl iodide 
• 91487-28-4 (2R,3R)-3-Acetoxy-3-furan-2-yl-2-methyl-propionic acid methyl ester 
• 85199-60-6 (R-(R^*,R^*))-β-hydroxy-α-methyl-2-furanpropanoate 
• 85199-55-9 methyl 3-(furan-2-yl)-2-methyl-3-oxopropanoate 
• 91487-35-3 (2S,3R)-2-Acetoxy-3-methyl-succinic acid dimethyl ester 

Downstream Products

• 85026-06-8 (2S,3R)-3-methylmalic acid 
• 80184-02-7 (2S,3S)-4-(benzyloxy)-3-methyl-1,2-butanediol 
• 95588-29-7 (4S)-4-<(1S)-2-(benzyloxy)-1-methylethyl>-2,2-dimethyl-1,3-dioxolane 
• 117155-77-8 (4S,5S)-6-Benzyloxy-1-[(2S,4S,6S,8R,9S)-8-((S)-sec-butyl)-4-(tert-butyl-dimethyl-silanyloxy)-9-methyl-1,7-dioxa-spiro[5.5]undec-10-en-2-yl]-4-(2-methoxy-ethoxymethoxy)-5-methyl-2-(toluene-4-sulfonyl)-hexan-3-ol 
• 117169-28-5 Trifluoro-methanesulfonic acid (2S,3S)-4-benzyloxy-1-[2-[(2R,4S,6S,8R,9S)-8-((S)-sec-butyl)-4-(tert-butyl-dimethyl-silanyloxy)-9-methyl-1,7-dioxa-spiro[5.5]undec-10-en-2-yl]-eth-(Z)-ylidene]-2-(2-methoxy-ethoxymethoxy)-3-methyl-butyl ester 
• 117169-27-4 (4S,5S)-6-Benzyloxy-1-[(2R,4S,6S,8R,9S)-8-((S)-sec-butyl)-4-(tert-butyl-dimethyl-silanyloxy)-9-methyl-1,7-dioxa-spiro[5.5]undec-10-en-2-yl]-4-(2-methoxy-ethoxymethoxy)-5-methyl-hexan-3-one 
• 117155-78-9 [(2R,4S,6S,8R,9S)-2-[(4S,5S)-6-Benzyloxy-4-(2-methoxy-ethoxymethoxy)-5-methyl-hex-2-ynyl]-8-((S)-sec-butyl)-9-methyl-1,7-dioxa-spiro[5.5]undec-10-en-4-yloxy]-tert-butyl-dimethyl-silane 
• 117155-76-7 (2S,3S)-4-Benzyloxy-2-(2-methoxy-ethoxymethoxy)-3-methyl-butyraldehyde 
• 86562-36-9 (2R,3R)-threo-2-methylpentane-1,3-diol 3-THP ether 1-tosylate 
• 86535-18-4 2-methyl-3-pentanol (S)-(-)-MTPA ester 
• 86535-19-5 2-methyl-3-pentanol (R)-(+)-MTPA ester 
• 86535-17-3 (2R,3R)-threo-2-methylpentane-1,3-diol 1-tosylate 
• 86562-34-7 (2R,3R)-threo-2-methylpentane-1,3-diol 1-benzyl ether 3-THP ether 
• 83997-86-8 serricornin acetate <(4S,6S,7S)-4,6-dimethyl-7-acetoxy-3-nonanone> 

Relevant articles and documents

Synthesis of a chiral building block for the C6?C9fragment of epothilones

A procedure has been developed for the synthesis of a new chiral building block for epothilone analogs starting from L-malic acid.

Chiral pool synthesis of N-Cbz-cis-(3R,4R)-3-methylamino-4-methylpiperidine from L-Malic acid

A new synthetic route to N-Cbz-cis-(3R,4R)-3-methylamino-4- methylpiperidine, key intermediate for CP- 690,550, was disclosed with L-malic acid as the chiral pool starting material. The title compound was obtained in 16 steps with a total yield of 26% and

The sex pheromone of the wasp spider Argiope bruennichi

(Figure Presented) Wasp spider looking for a mate: Female wasp spiders (see picture) use trimethyl methylcitrate as a volatile cue to attract males. The experiments were performed on a sunny meadow, showing for the first time that spider traps can be used to trap spiders in the field (photo: Helen Sandford).