281223-05-0

Basic information

• Product Name: endo-(4S)-2-oxo-4-isopropyl-4-phenyl-1,3,2-dioxathiolane
• CAS NO: 281223-05-0
• Molecular Weight: 226.296
• Mol File: 281223-05-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: endo-(4S)-2-oxo-4-isopropyl-4-phenyl-1,3,2-dioxathiolane(CAS DataBase Reference)
• NIST Chemistry Reference: endo-(4S)-2-oxo-4-isopropyl-4-phenyl-1,3,2-dioxathiolane(281223-05-0)
• EPA Substance Registry System: endo-(4S)-2-oxo-4-isopropyl-4-phenyl-1,3,2-dioxathiolane(281223-05-0)

Safety Data

• Hazardous Substances Data: 281223-05-0(Hazardous Substances Data)

Upstream product

• 51559-18-3 (S)-(-)-3-methyl-2-phenylbutane-1,2-diol 

Relevant articles and documents

Construction of a quaternary carbon center via cyclic sulfite

Reaction of (S)-2-oxo-4-methyl-4-phenyl-1,3,2-dioxathiolane with triethylaluminum selectively took place at the tertiary carbinol center to give (R)-2-methyl-2-phenyl-1-butanol. Enhanced stereoselectivity was obtained in a nonpolar solvent. Similarly, a series of (S)-4,4-disubstituted-1,3,2- dioxathiolanes reacted with trimethylaluminum to afford the corresponding (R)-2-alkyl-2-phenyl-1-propanols in good yields. (C) 2000 Elsevier Science Ltd.