281234-94-4

Upstream product

• 106-52-5 N-methyl-4-hydroxypiperidine 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 281234-95-5 methyl 4-(piperidin-4-yloxy)benzoate 

Downstream Products

• 718632-61-2 4-(1-methylpiperidin-4-yloxy)benzoic acid, hydrochloride 

Relevant academic research and scientific papers

SUBSTITUTED PYRROLO-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS

Compounds represented by formula (Ia) or (lb) and wherein R and R1 are as defined in the description, and pharmaceutically acceptable salts thereof, are disclosed; the said compounds are useful in the treatment of cell cycle proliferative disor

SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL) BENZOHETEROARYL COMPOUNDS

This invention is directed to an (aminoiminomethyl or aminomethyl) benzoheteroaryl compound of formula I which is useful for inhibiting the activity of Factor Xa by combining said compound with a composition containing Factor Xa. The present invention is also directed to compositions containing compounds of the formula I, methods for their preparation, their use, such as in inhibiting the formation of thrombin or for treating a patient suffering from, or subject to, a disease state associated with a physiologically detrimental excess amount of thrombin.