28125-87-3 Usage
Uses
Used in Pharmaceutical Industry:
Flutonidine is used as an antihypertensive agent for the treatment of hypertension. It helps in lowering blood pressure by activating alpha-2 adrenergic receptors, leading to decreased sympathetic nervous system activity, vasodilation, and reduced heart rate.
Additionally, Flutonidine is used as a potential therapeutic agent for managing pain and opioid withdrawal symptoms. Its mechanism of action involves the activation of imidazoline receptors, which may help in alleviating pain and reducing the severity of opioid withdrawal symptoms.
It is important to use flutonidine cautiously as it can cause side effects such as drowsiness, dizziness, and dry mouth. Furthermore, abrupt discontinuation of flutonidine can lead to rebound hypertension, so it should be tapered off gradually under medical supervision.
Check Digit Verification of cas no
The CAS Registry Mumber 28125-87-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,1,2 and 5 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 28125-87:
(7*2)+(6*8)+(5*1)+(4*2)+(3*5)+(2*8)+(1*7)=113
113 % 10 = 3
So 28125-87-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H12FN3/c1-7-2-3-8(11)6-9(7)14-10-12-4-5-13-10/h2-3,6H,4-5H2,1H3,(H2,12,13,14)
28125-87-3Relevant academic research and scientific papers
Process for producing amidine sulfonic acids
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, (2008/06/13)
An efficient synthesis of quanidines, e.g. of the formula (III), by oxidizing a thiourea, e.g. of the following formula (II): STR1 with H2 O2 and a molybdenum catalyst to yield an aminoiminomethane sulfonic acid which can then be reacted with an amine followed by optional transamination steps.
Propargyl-substituted 2-phenylamino-2-imidazolines and salts thereof
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, (2008/06/13)
Compounds of the formula STR1 wherein R1, R2 and R3, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, methyl, ethyl, methoxy or trifluoromethyl, and R4 and R5 are each hydrogen or propargyl, but other than both hydrogen or both propargyl at the same time, And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful as analgesics and hypotensives.
