28131-80-8Relevant academic research and scientific papers
DISAZO COMPOUNDS AND THEIR USE IN INK-JET PRINTING
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Paragraph 0098; 0099, (2013/03/26)
A compound of Formula (1) or a salt thereof: wherein: X is N or C(CN); Z is optionally substituted naphthyl; Ar is an aryl group carrying at least one substituent selected from the group consisting of an acetyl group, an acetate ester group, an amide group, a sulfonamide group, a sulfoxide group, a sulfone group, a phosphonate group, a nitrile group, an isonitrile group, a quaternary amine, a carbonyl group (other than a carboxylic acid), a polyhaloalkyl group or a halogen atom; and Ar may optionally be substituted with one or more further substituents. Also compositions, inks, printing processes, printed material and ink-jet cartridges.
IMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE
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Page/Page column 65, (2010/02/13)
There is provided an imidazole derivative useful as a thrombosis treating agent, which is represented by the formula (I): wherein R represents an optionally substituted cyclic hydrocarbon group or an optionally substituted heterocyclic group, W represents
SULFONAMIDE ENDOTHELIN ANTAGONISTS
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, (2008/06/13)
Compounds of the formula STR1 inhibit endothelin, wherein: one of X and Y is N and the other is O; R is naphthyl or naphthyl substituted with R. sup.1, R 2 and R 3 ;R 1, R 2 and R 3 are each independently hydrogen; alkyl, alkenyl, alkynyl, alkoxy, cycloalkyl, cycloalkylalkyl, cycloalkenyl, cycloalkenylalkyl, aryl, or aralkyl, any of which may be substituted with Z 1, Z 2 and Z 3 ; halo; hydroxyl; cyano; nitro;--C(O)H;--C(O)R 6 ; CO 2 H;--CO 2 R 6 ;--SH;--S(O) n R 6 ;--S(O) m--OH;--S(O). sub.m--OR 6 ;--O--S(O) m--R 6 ;--O--S(O) m OH;--O--S(O) m--OR. sup.6 ;--Z 4--NR 7 R 8 ; or--Z 4--N(R. sup.11)--Z 5--NR 9 R 10 ;R 4 and R 5 are each independently hydrogen; alkyl, alkenyl, alkynyl, alkoxy, cycloalkyl, cycloalkylalkyl, cycloalkenyl, cycloalkenylalkyl, aryl, or aralkyl, any of which may be substituted with Z 1, Z 2 and Z 3 ; halo; hydroxyl; cyano; nitro;--C(O)H;--C(O)R 6 ;--CO 2 H;--CO 2 R 6 ;--SH,--S(O) n R. sup.6 ;--S(O) m--OH;--S(O) m--OR 6 ;--O--S(O) m--R. sup.6 ;--O--S(O) m OH;--O--S(O) m--OR. sup.6 ;--Z 4--NR. sup.7 R 8 ;--Z 4--N(R. sup.11)--Z 5--NR. sup.9 R 10 ; or R 4 and R 5 together are alkylene or alkenylene (either of which may be substituted with Z 1, Z 2 and Z 3), completing a 4-to 8-membered saturated, unsaturated or aromatic ring together with the carbon atoms to which they are attached.
Discovery and structure-activity relationships of sulfonamide ET(A)- selective antagonists
Stein,Floyd,Bisaha,Dickey,Girotra,Gougoutas,Kozlowski,Lee,Liu,Malley,McMullen,Mitchell,Moreland,Murugesan,Serafino,Webb,Zhang,Hunt
, p. 1344 - 1354 (2007/10/02)
Random screening of compounds in an ETA receptor binding assay led to the discovery of a class of benzenesulfonamide ligands. Optimization led to the development of 5-amino-N-(3,4-dimethyl-5-isoxazolyl)-1- naphthalenesulfonamides which were functional ant
Process for the preparation of N-acetylaminoarylsulfonic acids in sulfuric acid as solvent
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, (2008/06/13)
The invention relates to salt-free N-acetylaminoarylsulfonic acids, their preparation by acetylation with acetic anhydride or acetyl chloride, sulfuric acid, which can also contain a small amount of water and/or dimethylformamide and/or N-methylpyrrolidone, serving as the solvent, and the use of the N-acetylaminoarylsulfonic acids for the preparation of their acid chlorides.
