28141-38-0 Usage
Uses
Used in Pharmaceutical Industry:
[methyl(phenyl)amino]methanesulfonic acid is used as a strong acid in the synthesis of various pharmaceuticals. Its unique chemical structure allows it to participate in numerous reactions, contributing to the development of new drugs and medications.
Used in Agrochemical Industry:
In the agrochemical sector, [methyl(phenyl)amino]methanesulfonic acid serves as a crucial intermediate in the production of various agrochemicals. Its strong acidic nature enables it to facilitate essential reactions, leading to the creation of effective agricultural products.
Used in Dye and Pigment Synthesis:
[methyl(phenyl)amino]methanesulfonic acid is also employed as an intermediate in the synthesis of dyes and pigments. Its versatile chemical structure allows for the production of a wide range of colors and shades, enhancing the options available in the dye and pigment market.
Used in Organic Synthesis:
[methyl(phenyl)amino]methanesulfonic acid is a valuable asset in organic synthesis, where it is used as a strong acid to facilitate various chemical reactions. Its presence in the reaction mixture can significantly influence the outcome, leading to the formation of desired products with improved efficiency and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 28141-38-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,1,4 and 1 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 28141-38:
(7*2)+(6*8)+(5*1)+(4*4)+(3*1)+(2*3)+(1*8)=100
100 % 10 = 0
So 28141-38-0 is a valid CAS Registry Number.
28141-38-0Relevant academic research and scientific papers
Carbonic anhydrase inhibitors. Diazenylbenzenesulfonamides are potent and selective inhibitors of the tumor-associated isozymes IX and XII over the cytosolic isoforms I and II
Carta, Fabrizio,Maresca, Alfonso,Scozzafava, Andrea,Vullo, Daniela,Supuran, Claudiu T.
experimental part, p. 7093 - 7099 (2010/03/03)
A series of diazenylbenzenesulfonamides, azo-dye derivatives of sulfanilamide or metanilamide incorporating phenol and amine moieties, were tested for inhibition of the tumor-associated isozymes of carbonic anhydrase (CA, EC 4.2.1.1), CA IX and XII. These compounds showed moderate-low inhibitory activities against the cytosolic isoforms CA I and II (offtargets) and excellent, low nanomolar inhibitory activity against the transmembrane CA IX and XII (KIs in the range of 3.5-63 nM against CA IX and 5.0-69.4 nM against CA XII, respectively). The selectivity ratio for inhibiting the tumor-associated CA IX over the offtarget CA II was in the range of 15-104 for these diazenylbenzenesulfonamides, making them among the most isoform-selective inhibitors targeting tumor-associated CAs (over the ubiquitous CA II). Since CA IX/XII were recently shown to be both therapeutic and diagnostic targets for hypoxic solid tumors overexpressing these proteins, such compounds held promise for the management of hypoxic tumors, which are largely non-responsible to classical chemo- and radio-therapy.
