28163-40-8 Usage
Uses
Possible impurity of Penbutolol (P220500). Non cytotoxic.
Check Digit Verification of cas no
The CAS Registry Mumber 28163-40-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,1,6 and 3 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 28163-40:
(7*2)+(6*8)+(5*1)+(4*6)+(3*3)+(2*4)+(1*0)=108
108 % 10 = 8
So 28163-40-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H18O2/c1-2-6-11(5-1)13-7-3-4-8-14(13)16-10-12-9-15-12/h3-4,7-8,11-12H,1-2,5-6,9-10H2
28163-40-8Relevant academic research and scientific papers
Design and synthesis of new potent, silent 5-HT(1A) antagonists by covalent coupling of aminopropanol derivatives with selective serotonin reuptake inhibitors
Perez,Pauwels,Pallard-Sigogneau,Fourrier,Chopin,Palmier,Colovray,Halazy
, p. 3423 - 3428 (2007/10/03)
Hybrid molecules built up by covalent coupling of aminopropanol derivatives (especially pindolol) with antidepressant drags like fluoxetine, paroxetine or milnacipran were found to be potent and silent 5-HT(1A) antagonists (K(B) 1 nM for 7c and 9a).