36507-48-9 Usage
Chemical Properties
White to Off-White Solid
Uses
Labelled Penbutolol (P220500). A β-adrenoceptor antagonist. Antihypertensive.
Enzyme inhibitor
This non-selective antihypertensive b-blocker (FW = 291.43 g/mol; CAS 36507-48-9; IUPAC: (S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)- propan-2-ol), known variously as Levatol?, Levatolol?, Lobeta?, Paginol?, Hostabloc?, and Betapressin, binds to both b1- and b2-adrenergic receptors, thus exhibiting the sympathomimetic effects of a partial b-adrenergic agonist, while also acting as a serotonin (5-HT1A) receptor antagonist. By blocking b-adrenergic receptors and the sympathetic nervous system, penbutolol decreases heart rate and cardiac output, thereby lowering arterial blood pressure.
Check Digit Verification of cas no
The CAS Registry Mumber 36507-48-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,5,0 and 7 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 36507-48:
(7*3)+(6*6)+(5*5)+(4*0)+(3*7)+(2*4)+(1*8)=119
119 % 10 = 9
So 36507-48-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H29NO2/c1-18(2,3)19-12-15(20)13-21-17-11-7-6-10-16(17)14-8-4-5-9-14/h6-7,10-11,14-15,19-20H,4-5,8-9,12-13H2,1-3H3/t15-/m0/s1