281666-28-2

Upstream product

• 281666-25-9 3,6-anhydro-1-O-benzyl-2-deoxy-4,5:7,8-di-O-isopropylidene-D-glycero-D-talo/galacto octitol 
• 281666-22-6 [(3aR,6R,6aS)-6-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-acetic acid ethyl ester 
• 281666-23-7 3,6-anhydro-2-deoxy-4,5:7,8-di-O-isopropylidene-D-glycero-D-talo/galacto octitol 
• 14131-84-1 2,3:5,6-di-O-isopropylidene-α-D-mannofuranose 
• 100-39-0 benzyl bromide 
• 281666-27-1 3,6-anhydro-1-O-benzyl-2-deoxy-4,5-O-isopropylidene-D-glycero-D-talo/galacto octitol 

Downstream Products

• 281666-21-5 3,6-anhydro-1-O-benzyl-2,7,8-trideoxy-D-talo/galacto-oct-7-enitol 

Relevant academic research and scientific papers

Pd(II)Cl2 mediated oxidative cyclisation of hydroxy-vinylfurans to lactols: Synthesis of Hagen's gland lactones

A concise synthesis of Hagen's gland lactones 3-6 by a chiron approach starting from D-mannose is described. Transformation of o-mannose to dihydroxy-vinylfuran 8 followed by Pd(II)Cl2 mediated oxidative cyclisation to obtain the tetrahydrofurofuran diol 7 constituted the key reaction in the total synthesis of 3-6. (C) 2000 Elsevier Science Ltd.