28180-80-5

Usage

Uses

Used in Pharmaceutical Development:
2,2,2-Trichloroethyl3-methyl-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate is used as a starting material for the synthesis of pharmaceutical drugs. Its complex structure and functional groups make it a promising candidate for the development of new therapeutic agents.
Used in Chemical Synthesis:
In the chemical industry, 2,2,2-Trichloroethyl3-methyl-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate is used as an intermediate in the synthesis of other organic compounds. Its versatile structure allows for further modification and functionalization, making it a valuable component in the creation of a wide range of chemical products.
Used in Laboratory Research:
2,2,2-Trichloroethyl3-methyl-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate is used as a research compound in controlled laboratory environments. Its unique properties and potential applications make it an interesting subject for scientific investigation, particularly in the fields of organic chemistry and pharmacology.
Due to the complex and specialized nature of 2,2,2-Trichloroethyl3-methyl-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicydo[4.2.0]oct-2-ene-2-carboxylate, it requires careful handling and is typically used by trained professionals in controlled laboratory settings.

Upstream product

• 39879-59-9 2,2,2-trichloroethyl (1S,3S,5R,6R)-6-phenylacetamido-2,2-dimethylpenam-3-carboxylate, 1-oxide 
• 30200-16-9 (6R,7R)-3-Methyl-5,8-dioxo-7-phenylacetylamino-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 2,2,2-trichloro-ethyl ester 

Downstream Products

• 49811-08-7 (5R)-2-isopropenyl-7-oxo-6t-(2-phenyl-acetylamino)-(5rH)-4-thia-1-aza-bicyclo[3.2.0]heptane-2c,3t-dicarboxylic acid 3-ethyl ester 2-(2,2,2-trichloro-ethyl) ester 
• 57630-37-2 (6R)-3-methyl-7t-(2-phenyl-acetylamino)-8-thioxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 2,2,2-trichloro-ethyl ester 
• 63853-61-2 (2S,6R,7R)-2,2,2-trichloroethyl 2-methoxy-3-methyl-7-phenylacetamidoceph-3-em-4-carboxylate 
• 99407-35-9 2,2,2-trichloroethyl 5-methylthiazole-4-carboxylate 
• 99407-37-1 2,2,2-trichloroethyl 2-methoxycarbonyl-5-methylthiazole-4-carboxylate 
• 99407-38-2 methyl α-methoxy-5-methyl-α-phenylacetamido-4-(2,2,2-trichloroethoxycarbonylthiazol)-2-ylacetate 
• 33513-04-1 2,2,2-trichloroethyl 7β-phenylacetamido-3-methyl-3-cephem-4-carboxylate 1R-(α)-oxide 
• 33465-39-3 2,2,2-trichloroethyl 7β-phenylacetamido-3-methyl-3-cephem-4-carboxylate 1S-(β)-oxide 
• 83901-02-4 2,2,2-trichloroethyl 7β-phenylacetamido-3-methyl-3-cephem-4-carboxylate 1,1-dioxide 
• 99407-32-6 2,2,2-trichloroethyl 2-formyl-5-methylthiazole-4-carboxylate 
• 89044-93-9 2,2,2-trichloroethyl 5-methyl-2-phenylacetamidocarbonylthiazole 4-carboxylate monohydrate 
• 99407-31-5 2,2,2-trichloroethyl 2--5-methylthiazole-4-carboxylate 
• 99407-34-8 2,2,2-trichloroethyl 2-aminocarbonyl-5-methylthiazole-4-carboxylate 
• 33465-54-2 2,2,2-trichloroethyl (1S,6R,7R)-3-bromomethyl-7-phenylacetamidoceph-3-em-4-carboxylate 1-oxide 

Relevant academic research and scientific papers

A new and convenient reduction of cephalosporin sulphoxides

A new, convenient and good yield reduction of cephalosporin S(β)-sulphoxides to the corresponding sulphides was achieved upon treatment with iodotrimethylsilane (TMSI) in dichloromethane.

CEPHALOSPORINS. PART III. REARRANGEMENTS OF 6-HALOPENICILLIN 1-OXIDES INTO 7-HALOCEPHALOSPORANIC ACIDS

Rearrangements of 6-halopenicillin 1-oxides into respective 7-halocephalosporanic acids in presence of typical catalysts of transformation, basic catalysts and without catalysts are described.