33465-39-3

Upstream product

• 28180-80-5 (6R,7R)-2,2,2-trichloroethyl 3-methyl-7-phenylacetamidoceph-3-em-4-carboxylate 
• 85954-90-1 2,2,2-trichloroethyl(1R,2R,6R,7R)-2-bromo-3-methyl-7-phenylacetamidoceph-3-em-4-carboxylate 1-oxide 

Downstream Products

• 61365-01-3 2,2,2-trichloroethyl 7β-phenylacetamido-2-methylene-3-methyl-3-cephem-4-carboxylate 1-oxide 
• 85954-90-1 2,2,2-trichloroethyl(1R,2R,6R,7R)-2-bromo-3-methyl-7-phenylacetamidoceph-3-em-4-carboxylate 1-oxide 
• 33465-54-2 2,2,2-trichloroethyl (1S,6R,7R)-3-bromomethyl-7-phenylacetamidoceph-3-em-4-carboxylate 1-oxide 
• 33465-55-3 2,2,2-trichloroethyl(1S,2'RS,6R,7R)-3-bromomethyl-7-(2'-bromophenylacetamido)ceph-3-em-4-carboxylate 1-oxide 
• 33465-52-0 2,2,2-trichloroethyl(1S,2'RS,6R,7R)-7-(2'-bromophenyl-acetamido)-3-methylceph-3-em-4-carboxylate 1-oxide 
• 61365-04-6 C₃₂H₂₇Cl₃N₂O₅S 
• 61365-04-6 C₃₂H₂₇Cl₃N₂O₅S 
• 61710-66-5 2,2,2-trichloroethyl 7β-phenylacetamido-2-spiro-cyclopropyl-3-methyl-3-cephem-4-carboxylate 1-oxide 

Relevant academic research and scientific papers

SYNTHESIS AND 1,3-DIPOLAR CYCLOADDITIONS OF 2-METHYLENECEPHALOSPORINS

Cephalosporin R- and S-sulphoxides were prepared.The S-sulphoxides gave Mannich-reaction resulting in the formation of 2-methylenecephalosporins.These electrom-deficient dienes underwent 1,3-dipolar cycloadditions with diazoalkanes in a chemo- and regiosp

Photoinitiated bromination of 3-methylceph-3-em 1S-oxide esters. A convenient synthesis of 3-substituted cephalosporins from penicillins

Photoinitiated bromination of 3-methyl-ceph-3-em 1S-oxide esters 2, readily obtained from penicillins, gave the corresponding 3-bromomethyl derivatives 5. The 3-bromomethyl 1S-oxides 5b and 5c were converted into the salts 12 and 13 of the 3-methylthiomet