28180-92-9Relevant articles and documents
Synthesis and biochemical evaluation of cephalosporin analogues equipped with chemical tethers
Duhme-Klair, Anne-Kathrin,Gyulev, Ivan,Herman, Reyme,Krauss, Thomas F.,Miller, Lisa M.,Thomas, Gavin H.
, p. 36485 - 36494 (2020/10/28)
Molecular probes typically require structural modifications to allow for the immobilisation or bioconjugation with a desired substrate but the effects of these changes are often not evaluated. Here, we set out to determine the effects of attaching functio
Synthesis of potential impurities of cefalexin and cefradine
Hendrix,Roets,Bervoets,Thomas,Pijcke,Busson,Janssen,Hoogmartens
, p. 215 - 219 (2007/10/02)
The synthesis of some impurities of the cephalosporin antibiotics cefalexin and cefradine is described. These impurities which may be present in commercial samples are formed during the semi-synthetic preparation of these antibiotics or upon their degradation. The preparation of these compounds enables the validation of selective quantitative analytical methods, such as column liquid chromatography and thin layer chromatography.