33125-05-2Relevant articles and documents
Stille coupling of stereochemically defined α- sulfonamidoorganostannanes
Kells, Kevin W.,Chong, J. Michael
, p. 15666 - 15667 (2004)
Addition of tributylstannylmetallics to (R)-tert-butanesulfonimine derivatives of arylaldehydes provides α-sulfinamidostannanes with high (>98% de) diastereoselectivities. Oxidation of these compounds with m-CPBA gives α-sulfonamidostannanes which undergo Pd/Cu-catalyzed Stille-type couplings with benzoyl chloride. Best yields are achieved using the electron-rich tris(2,4,6-trimethoxyphenyl)phosphine as the ligand. Inversion of configuration at the benzylic carbon is observed. Copyright
Synthesis ofN-Boc-α-amino Acids from Carbon Dioxide by Electrochemical Carboxylation ofN-Boc-α-aminosulfones
Senboku, Hisanori,Minemura, Yoshihito,Suzuki, Yuto,Matsuno, Hidetoshi,Takakuwa, Mayu
, p. 16077 - 16083 (2021/10/12)
Electrochemical reduction ofN-Boc-α-aminosulfones in DMF using an undivided cell equipped with a Pt plate cathode and an Mg rod anode under atmospheric pressure of bubbling carbon dioxide through the solution under constant current conditions resulted in a reductive C-S bond cleavage with elimination of benzenesulfinate ion generating the corresponding anion species followed by fixation of carbon dioxide to give the correspondingN-Boc-α-amino acids in moderate to good yields.
Anti-amyotrophic lateral sclerosis effect of thiourea homologues compound
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Paragraph 0007-0008, (2020/12/30)
The invention relates to an anti-amyotrophic lateral sclerosis effect of a thiourea homologues compound, and belongs to the technical field of motor neuron disease treatment. The technical problem tobe solved by the invention is that the thiourea homologues compound has the effect of resisting amyotrophic lateral sclerosis. The structure of the compound is shown as the description, and the compound has the effect of resisting amyotrophic lateral sclerosis.