28192-10-1

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-chlorophenyl)-2,5-dihydro-1H-pyrrole is used as a potential medicinal compound for its potential biological activities. It may act as a ligand for specific receptors or enzymes, making it a promising candidate for the development of new drugs.
Used in Organic Synthesis:
1-(4-chlorophenyl)-2,5-dihydro-1H-pyrrole is used as a building block in organic synthesis due to its unique structure and reactivity, allowing for the creation of more complex molecules with specific properties.
Used in Chemical Research:
1-(4-chlorophenyl)-2,5-dihydro-1H-pyrrole is used as a subject of study in chemical research to better understand its properties, reactivity, and potential applications in various fields, including material science and medicinal chemistry.

Upstream product

• 30438-94-9 N,N-diallyl-4-chlorobenzenamine 

Downstream Products

• 5044-38-2 1-(4-chlorophenyl)-1H-pyrrole 

Relevant academic research and scientific papers

Highly efficient Ru(ii)-alkylidene based Hoveyda-Grubbs catalysts for ring-closing metathesis reactions

Three novel phosphine-free Ru-alkylidenes (7a-7c) have been synthesized and utilized as efficient catalysts for ring closing metathesis (RCM) reaction. Spectroscopic data, i.e. NMR and HRMS, along with single crystal X-ray diffraction analysis, were used

Synthesis of pyrrole derivatives from diallylamines by one-pot tandem ring-closing metathesis and metal-catalyzed oxidative dehydrogenation

A series of aryl-substituted pyrrole derivatives was synthesized from diallylamines through a ruthenium carbene catalyzed ring-closing metathesis reaction and in situ oxidative dehydrogenation reaction catalyzed by FeCl 3·6H2O or CuCl2·2H2O in the presence of O2. The reaction was mild, simple, and convenient. An oxygen atmosphere played a critical role in obtaining high conversion of substituted pyrroles in the proposed catalytic system.

Assisted tandem catalytic RCM-aromatization in the synthesis of pyrroles and furans

An assisted tandem catalytic transformation of diallyl amines and diallyl ethers into N-aryl pyrroles and furans, respectively, is described. The sequence relies on ring closing metathesis followed by dehydrogenation of the initially formed dihydropyrroles and dihydrofurans. Both steps are Ru-catalyzed, but the sequence requires only one precatalyst, because conversion of the metathesis catalyst into the dehydrogenation catalyst is achieved in situ, triggered by the oxidant tert-butyl hydroperoxide.