28192-10-1

Basic information

• Product Name: 1-(4-chlorophenyl)-2,5-dihydro-1H-pyrrole
• CAS NO: 28192-10-1
• Molecular Formula: C₁₀H₁₀ClN
• Molecular Weight: 179.6461
• Mol File: 28192-10-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 289.4°C at 760 mmHg
• Flash Point: 128.8°C
• Density: 1.204g/cm³
• Vapor Pressure: 0.0022mmHg at 25°C
• Refractive Index: 1.598
• CAS DataBase Reference: 1-(4-chlorophenyl)-2,5-dihydro-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)-2,5-dihydro-1H-pyrrole(28192-10-1)
• EPA Substance Registry System: 1-(4-chlorophenyl)-2,5-dihydro-1H-pyrrole(28192-10-1)

Safety Data

• Hazardous Substances Data: 28192-10-1(Hazardous Substances Data)

Usage

General Description

1-(4-chlorophenyl)-2,5-dihydro-1H-pyrrole is a chemical compound that belongs to the class of pyrrole derivatives. It is a substituted pyrrole with a 4-chlorophenyl group attached to the first position of the pyrrole ring. 1-(4-chlorophenyl)-2,5-dihydro-1H-pyrrole has potential applications in the pharmaceutical industry due to its potential biological activities. It may act as a ligand for specific receptors or enzymes, and has been studied for its potential medicinal properties. Additionally, it may also have applications in organic synthesis and chemical research due to its unique structure and reactivity. Overall, 1-(4-chlorophenyl)-2,5-dihydro-1H-pyrrole is a versatile compound with potential applications in various fields.

Upstream product

• 30438-94-9 N,N-diallyl-4-chlorobenzenamine 

Downstream Products

• 5044-38-2 1-(4-chlorophenyl)-1H-pyrrole 

Relevant articles and documents

Highly efficient Ru(ii)-alkylidene based Hoveyda-Grubbs catalysts for ring-closing metathesis reactions

Three novel phosphine-free Ru-alkylidenes (7a-7c) have been synthesized and utilized as efficient catalysts for ring closing metathesis (RCM) reaction. Spectroscopic data, i.e. NMR and HRMS, along with single crystal X-ray diffraction analysis, were used

Assisted tandem catalytic RCM-aromatization in the synthesis of pyrroles and furans

An assisted tandem catalytic transformation of diallyl amines and diallyl ethers into N-aryl pyrroles and furans, respectively, is described. The sequence relies on ring closing metathesis followed by dehydrogenation of the initially formed dihydropyrroles and dihydrofurans. Both steps are Ru-catalyzed, but the sequence requires only one precatalyst, because conversion of the metathesis catalyst into the dehydrogenation catalyst is achieved in situ, triggered by the oxidant tert-butyl hydroperoxide.