2820-55-5 Usage
Description
(2''S)-Nicotine-1-oxide is a metabolite of nicotine . It is formed when nicotine is metabolized in the liver by cytochrome P450 (CYP) isoform CYP2A6. (2''S)-Nicotine-1-oxide has been detected in human sperm and semen.
Chemical Properties
Light Yellow Crystals
Uses
Different sources of media describe the Uses of 2820-55-5 differently. You can refer to the following data:
1. Nicotine-1’-N-oxide is a derivative of nicotine found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as metabolites of nicotine in animals and in man. The metabolism of nicotine i
2. Nicotine-1’-N-oxide is a derivative of Nicotine (N412420) found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as metabolites of nicotine in animals and in man. The metabolism of nicotine in man proceeds by alternative routes of oxidation of nitrogen to form nicotine-1’-N-oxide (both diastereomers) or cotinine. The ratio of these two products has been suggested as an indicator of bladder cancer in humans.
Definition
ChEBI: A member of the class of pyridine N-oxides obtained by oxidation of the pyridine nitrogen of (S)-nicotine.
Check Digit Verification of cas no
The CAS Registry Mumber 2820-55-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,2 and 0 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2820-55:
(6*2)+(5*8)+(4*2)+(3*0)+(2*5)+(1*5)=75
75 % 10 = 5
So 2820-55-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2O/c1-11-6-3-5-10(11)9-4-2-7-12(13)8-9/h2,4,7-8,10H,3,5-6H2,1H3
2820-55-5Relevant articles and documents
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Phillipson,Handa
, p. 2683 (1975)
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6-Pyridylnicotine and bis-6,6'-nicotine - new chiral 2,2'-bipyridines
Schmidt, Boris,Neitemeier, Vera
, p. 42 - 44 (2007/10/03)
Starting from (-)-nicotine, two new 2,2'-bipyridine ligands 6 and 7 with chiral pyrrolidine side chains have been synthesized. The stoichiometric complexation by palladium(II) or mercury(II) ions gives the bipyridyl complexes 8 and 9.
