282109-03-9Relevant academic research and scientific papers
The reaction of 1,2-diones with ureas - A synthesis of 4-(1-substituted)alkylimidazol-2-ones
Liepa, Andris J.,Wright, Denis M.J.
, p. 73 - 76 (2000)
The reaction between glyoxal and ureas or thioureas in formic acid in the presence of sulfmates gives 4-arylsulfonylimidazol-2-ones such as (3b) and (3e). Labile 4-arylsulfonyl-5-hydroxyimidazolidin-2-ones (2a-c) may be isolated. Acyclic or cyclic 1,2-diketones react with ureas in the presence of selected nucleophiles to give side-chain substituted imidazol-2-ones (5a-e). CSIRO 2000.
