2823-52-1 Usage
General Description
Uridine, 2'-deoxy-5-fluoro-, 5'-acetate is a modified form of uridine, a nucleoside that plays a crucial role in RNA and DNA synthesis. The addition of a 5'-acetate group to uridine's 2'-deoxy-5-fluoro structure alters its biological and chemical properties. This modified chemical compound has been studied for its potential therapeutic applications, particularly in the treatment of certain types of cancer and viral infections. It is also of interest in the field of medicine for its potential use as a pharmaceutical agent. Understanding the pharmacological properties and potential applications of this compound is an important area of research for the development of novel treatments for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 2823-52-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,2 and 3 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2823-52:
(6*2)+(5*8)+(4*2)+(3*3)+(2*5)+(1*2)=81
81 % 10 = 1
So 2823-52-1 is a valid CAS Registry Number.
2823-52-1Relevant articles and documents
Regioselective acylation of nucleosides and their analogs catalyzed by Pseudomonas cepacia lipase: enzyme substrate recognition
Li, Ning,Zong, Min-Hua,Ma, Ding
supporting information; experimental part, p. 1063 - 1068 (2009/04/11)
The substrate recognition of Pseudomonas cepacia lipase in the acylation of nucleosides was investigated by means of rational substrate engineering for the first time. P. cepacia lipase displayed excellent 3′-regioselectivities (96 to >99%) in the lauroyl
Enzymatic regioselective acylation of the 3′-hydroxyl groups of 2′-deoxy-5-fluorouridine (FUdR) and 2′-Deoxy-5-trifiuoromethyluridine (CF3UdR)
Nozaki, Kenji,Uemura, Atuhiko,Yamashita, Jun-Ichi,Yasumoto, Mitsugi
, p. 7327 - 7328 (2007/10/02)
A lipase from Pseudomonas sp. (Amano PS) catalyzes regioselecfive acylation of the 3′-hydroxyl groups of FUdR and CF3UdR.
