2823-52-1 Usage
Uses
Used in Pharmaceutical Industry:
Uridine, 2'-deoxy-5-fluoro-, 5'-acetate is used as a pharmaceutical agent for its potential therapeutic applications in treating certain types of cancer and viral infections. Its unique chemical structure allows for targeted interactions with biological systems, offering new avenues for disease management and treatment.
Used in Cancer Treatment:
In the field of oncology, Uridine, 2'-deoxy-5-fluoro-, 5'-acetate is utilized as a therapeutic agent for its potential to inhibit cancer cell growth and proliferation. Its modified structure may disrupt essential cellular processes in cancer cells, leading to their death or reduced ability to divide and spread.
Used in Antiviral Therapy:
Uridine, 2'-deoxy-5-fluoro-, 5'-acetate is also considered for use in antiviral therapy, where it may interfere with viral replication and assembly processes. Its incorporation into viral nucleic acids could lead to the production of non-functional viral particles, thereby limiting the spread of infection.
Used in Research and Development:
In the scientific community, Uridine, 2'-deoxy-5-fluoro-, 5'-acetate serves as an important research tool for studying the mechanisms of RNA and DNA synthesis, as well as the development of novel antiviral and anticancer drugs. Its unique properties provide insights into the fundamental processes of nucleic acid metabolism and the potential for targeted therapeutic interventions.
Overall, the exploration of Uridine, 2'-deoxy-5-fluoro-, 5'-acetate's pharmacological properties and potential applications is a crucial area of research, with the aim of developing innovative treatments for a variety of diseases, particularly cancer and viral infections.
Check Digit Verification of cas no
The CAS Registry Mumber 2823-52-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,2 and 3 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2823-52:
(6*2)+(5*8)+(4*2)+(3*3)+(2*5)+(1*2)=81
81 % 10 = 1
So 2823-52-1 is a valid CAS Registry Number.
2823-52-1Relevant academic research and scientific papers
Regioselective acylation of nucleosides and their analogs catalyzed by Pseudomonas cepacia lipase: enzyme substrate recognition
Li, Ning,Zong, Min-Hua,Ma, Ding
supporting information; experimental part, p. 1063 - 1068 (2009/04/11)
The substrate recognition of Pseudomonas cepacia lipase in the acylation of nucleosides was investigated by means of rational substrate engineering for the first time. P. cepacia lipase displayed excellent 3′-regioselectivities (96 to >99%) in the lauroyl
Regioselective acylation of nucleosides catalyzed by candida antarctica lipase B: Enzyme substrate recognition
Li, Ning,Zong, Min-Hua,Ma, Ding
supporting information; scheme or table, p. 5375 - 5378 (2009/05/07)
The substrate recognition of Candida antarctica lipase B (CAL-B) in the acylation of nucleosides was revealed through rational substrate engineering for the first time. CAL-B displayed lower activities and excellent 5′-regioselectivities (94 to >99%) in t
Enzymatic regioselective acylation of the 3′-hydroxyl groups of 2′-deoxy-5-fluorouridine (FUdR) and 2′-Deoxy-5-trifiuoromethyluridine (CF3UdR)
Nozaki, Kenji,Uemura, Atuhiko,Yamashita, Jun-Ichi,Yasumoto, Mitsugi
, p. 7327 - 7328 (2007/10/02)
A lipase from Pseudomonas sp. (Amano PS) catalyzes regioselecfive acylation of the 3′-hydroxyl groups of FUdR and CF3UdR.
