28240-71-3

Basic information

• Product Name: 1,4-BIS(DICHLOROPHOSPHINO)BUTANE
• Synonyms: 1,4-BIS(DICHLOROPHOSPHINO)BUTANE
• CAS NO: 28240-71-3
• Molecular Formula: C₄H₈Cl₄P₂
• Molecular Weight: 259.865842
• Mol File: 28240-71-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 119-123 °C(Press: 2.5 Torr)
• Appearance: /
• CAS DataBase Reference: 1,4-BIS(DICHLOROPHOSPHINO)BUTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-BIS(DICHLOROPHOSPHINO)BUTANE(28240-71-3)
• EPA Substance Registry System: 1,4-BIS(DICHLOROPHOSPHINO)BUTANE(28240-71-3)

Safety Data

• Hazardous Substances Data: 28240-71-3(Hazardous Substances Data)

Usage

General Description

1,4-Bis(dichlorophosphino)butane is an organophosphorus compound with the chemical formula C8H16Cl4P2. It is a white solid with a strong odor and is used as a ligand in coordination chemistry to form metal complexes. 1,4-BIS(DICHLOROPHOSPHINO)BUTANE is commonly used as a catalyst or co-catalyst in organic synthesis, particularly in asymmetric catalysis. It is also used in the production of flame retardants and phosphorus-containing polymers. Due to its phosphorus content, 1,4-Bis(dichlorophosphino)butane can pose health risks if not handled properly, and exposure should be minimized to prevent any adverse effects.

Upstream product

• 5518-64-9 1,4-diphosphinobutane 
• 110-52-1 1,4-dibromo-butane 
• 23708-47-6 1,4-bis(bromomagnesium)butane 
• 86926-30-9 1,4-Butandiylbis 
• 91635-29-9 Diethyl Tetramethylenebis(phosphonite) 

Downstream Products

• 1620210-67-4 1,4-bis[bis(pentafluorophenyl)phosphino]butane 
• 222017-54-1 1,4-di(di-p-methoxyphenylphosphino)butane 
• 222017-56-3 1,4-bis[bis(4-fluorophenyl)phosphino]butane 

Relevant articles and documents

Branch-selective, Iridium-catalyzed hydroarylation of monosubstituted alkenes via a cooperative destabilization strategy

Highly branch-selective, carbonyl-directed hydroarylations of monosubstituted alkenes are described. The chemistry relies upon a cationic Ir(I) catalyst modified with an electron deficient, wide bite angle bisphosphine ligand. This work provides a regioisomeric alternative to the Murai hydroarylation protocol.

Preparation of polyfunctional phosphines using zinc organometallics

The reaction of functionalized diorganozincs with chlorodiorganophosphines provides polyfunctional phosphines in good yields. Especially attractive is the hydroboration/boron-zinc exchange sequence which allows the conversion of functionalized olefins into polyfunctional phosphines in a one-pot procedure. Several new chiral phosphines have been prepared starting from readily available chiral olefins (terpenes) and their efficiency in asymmetric hydrogenation reactions has been evaluated.