28240-71-3

Usage

Uses

Used in Coordination Chemistry:
1,4-BIS(DICHLOROPHOSPHINO)BUTANE is used as a ligand for forming metal complexes, which is crucial in coordination chemistry. Its ability to bind with metal ions allows for the creation of stable and functional complexes with various applications in chemical research and industry.
Used in Organic Synthesis:
1,4-BIS(DICHLOROPHOSPHINO)BUTANE is used as a catalyst or co-catalyst in organic synthesis, particularly enhancing the efficiency and selectivity of asymmetric catalysis. This role is vital for producing enantiomerically pure compounds, which are essential in pharmaceuticals and agrochemicals where stereochemistry significantly influences biological activity.
Used in Flame Retardant Production:
In the flame retardant industry, 1,4-BIS(DICHLOROPHOSPHINO)BUTANE is used as a component in the synthesis of flame retardants. Its phosphorus content contributes to the fire-resistant properties of materials, making it a valuable additive in various products to improve safety standards.
Used in Polymer Production:
1,4-BIS(DICHLOROPHOSPHINO)BUTANE is utilized in the production of phosphorus-containing polymers, which exhibit unique properties such as flame retardancy and enhanced thermal stability. These polymers find applications in various industries, including plastics, textiles, and coatings, where performance and safety are paramount.
Health and Safety Considerations:
Due to the presence of phosphorus and dichlorophosphino groups, 1,4-Bis(dichlorophosphino)butane can pose health risks if not handled properly. It is essential to minimize exposure and implement appropriate safety measures during its use to prevent any adverse effects on human health and the environment.

Upstream product

• 91635-29-9 Diethyl Tetramethylenebis(phosphonite) 
• 86926-30-9 1,4-Butandiylbis 
• 5518-64-9 1,4-diphosphinobutane 
• 110-52-1 1,4-dibromo-butane 
• 23708-47-6 1,4-bis(bromomagnesium)butane 

Downstream Products

• 1620210-67-4 1,4-bis[bis(pentafluorophenyl)phosphino]butane 
• 222017-54-1 1,4-di(di-p-methoxyphenylphosphino)butane 
• 222017-56-3 1,4-bis[bis(4-fluorophenyl)phosphino]butane 

Relevant academic research and scientific papers

Branch-selective, Iridium-catalyzed hydroarylation of monosubstituted alkenes via a cooperative destabilization strategy

Highly branch-selective, carbonyl-directed hydroarylations of monosubstituted alkenes are described. The chemistry relies upon a cationic Ir(I) catalyst modified with an electron deficient, wide bite angle bisphosphine ligand. This work provides a regioisomeric alternative to the Murai hydroarylation protocol.

A new method for the synthesis of dichlorophosphines

A new method for the synthesis of alkyldichlorophosphines by chlorination of alkylphosphines with phosphorus pentachloride under mild conditions is described.

Preparation of polyfunctional phosphines using zinc organometallics

The reaction of functionalized diorganozincs with chlorodiorganophosphines provides polyfunctional phosphines in good yields. Especially attractive is the hydroboration/boron-zinc exchange sequence which allows the conversion of functionalized olefins into polyfunctional phosphines in a one-pot procedure. Several new chiral phosphines have been prepared starting from readily available chiral olefins (terpenes) and their efficiency in asymmetric hydrogenation reactions has been evaluated.

ZUR KENNTNIS DER ORGANOPHOSPHORVERBINDUNGEN XX. Bifunktionelle Aminophosphane (Et2N)2P-n-P(NEt2)2 und Et2N(R)P-n-P(R)NEt2

Bifunctional aminophosphanes (Et2N)2P-n-P(NEt2)2 (n = 1-10) (1) and Et2NP(R)-n-P(R)NEt2 (n = 2-4, R = Alkyl, Ph) (2), which are valuable intermediates in organophosphorus synthesis, are obtained by two methods.Because of the marked nucleophility of phosphorus in 1 and 2, reactions with Lewis acids take place very smoothly as is shown by preparation of (Et2N)2P(X)-4-(X)P(NEt2)2 (X = O, S, Se, Te, BH3, BBr3) and 4-(CH3)P(NEt2)2>2+2I-.Fission of P-N bonds by PCl3, MeOH, H2S and CS2 affords Cl2P-4-PCl2, (MeO)2P-4-P(OMe)2, (MeO)Et2NP-4-PNEt2(OMe), the dithiophosphinate 4-(H)PS2>2-2 Et2NH2+, and the dithiocarbaminate 2P-4-P2.The 31P/1H/NMR-Spectra are discussed especially with regard to steric aspects in the synthesis of the chiral compounds 2 and their derivatives.