2826-30-4

Usage

Uses

Used in Organic Synthesis:
(2-nitrobenzylidene)propanedinitrile is used as a precursor in the synthesis of various organic molecules and materials. Its unique structure allows for the creation of a wide range of compounds with diverse applications.
Used in Organic Electronics:
(2-nitrobenzylidene)propanedinitrile is utilized in the field of organic electronics due to its potential applications in the development of organic optoelectronic devices. Its properties make it a promising building block for constructing such devices.
Used in Advanced Materials Development:
(2-nitrobenzylidene)propanedinitrile's unique chemical structure and properties make it a valuable tool in the development of advanced materials and technologies, contributing to the creation of innovative solutions in various industries.
Safety Note:
It is important to handle (2-nitrobenzylidene)propanedinitrile with care, as it is known to be hazardous if not properly managed. Proper safety measures should be taken to ensure the safe use and handling of this chemical compound.

Upstream product

• 612-25-9 2-Nitrobenzyl alcohol 
• 92437-70-2 C₁₅H₁₂N₂O₃ 
• 109-77-3 malononitrile 
• 552-89-6 2-nitro-benzaldehyde 

Downstream Products

• 94988-65-5 7‐amino‐5‐(2‐nitrophenyl)‐6‐cyano-5H‐pyrano[2,3‐d]pyrimidin‐(1H,3H)‐2,4-dione 
• 1431657-36-1 methyl 4-(tert-butylamino)-3,3-dicyano-2-(2-nitrophenyl)-5-(trifluoromethyl)cyclopenta-1,4-dienecarboxylate 
• 1431657-49-6 methyl 4-(tert-butylamino)-3,3-dicyano-2-(2-nitrophenyl)-5-(pentafluoroethyl)cyclopenta-1,4-dienecarboxylate 
• 1431621-33-8 6-amino-1-((1,3-diphenyl-1H-pyrazole-4-yl)methyleneamino)-4-(2-nitrophenyl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile 
• 7143-42-2 methyl 2-((methoxycarbonyl)amino)benzoate 
• 89607-33-0 6-amino-4-(2-nitrophenyl)-3-methyl-2,4-dihydropyrano[2,3-c] pyrazole-5-carbonitrile 
• 75825-37-5 2-cyano-3-(2-nitrophenyl)prop-2-enamide 

Relevant academic research and scientific papers

Β-Cyclodextrin as a Biomimetic Catalyst for the Efficient Synthesis of 4-Oxo-pyrido[1,2-a] Pyrimidine-3-Carbonitrile in Aqueous Medium

Abstract: Supramolecular β-cyclodextrin as a highly efficient, biodegradable, and reusable catalyst for the synthesis of 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbonitrile derivatives (4a–s) is investigated via a cascade reaction of aldehydes, malanonitrile

Synthesis of novel spiro-oxazino-quinoline derivatives and study of their photophysical properties

A convenient route was successfully developed for the synthesis of novel heterocycles such as spiro-oxazino-quinoline derivatives from 2-aminoquinoline-3-carbonitrile (4) in good yield. The Spiro-quinoline derivatives (6, 8 and 10) were synthesized and fu

Tuning regioisomer reactivity in catalysis using bifunctional metal-organic frameworks with mixed linkers

The activity of two bifunctional metal-organic frameworks (MOFs) with IRMOF-9 topology that contain amino, phosphine oxide and methyl groups is described. The amino group acts as an active site for the Knoevenagel condensation of ortho, meta or para nitro

Successive oxidation-condensation reactions using a multifunctional gold-supported nanocomposite (Au/MgCe-HDO)

The application of gold-supported nanocomposites is useful in clinical diagnostics because of their ability to provide bio-compatible and sensitive detection systems. A gold-supported magnesium hydroxide and cerium oxide nanocomposite framework (Au/MgCe-HDO) was synthesized and characterized via XRD, XPS, SEM, DLS, TEM, and TGA techniques. The nanocomposite was used as a selective catalyst for the aerobic oxidation of alcohols under mild reaction conditions followed by successive condensation reactions, like Knoevenagel and Claisen-Schmidt condensation. Substituted benzyl alcohols were converted into the corresponding carbonyl compounds in the presence of the Au/MgCe-HDO nanocomposite with O2 gas and toluene as a solvent. We observed that, upon the addition of malononitrile/ethyl cyanoacetate/acetophenone to the catalyst in the aerobic oxidation reaction, the reaction proceeds to produce the corresponding desired condensation product with up to 95% yield.

Introduction of bis-imidazolium dihydrogen phosphate as a new green acidic ionic liquid catalyst in the synthesis of arylidene malononitrile, ethyl (E)-3-(aryl)-2-cyanoacrylate and tetrahydrobenzo[b]pyran derivatives

In this work, [H2-Bisim][H2PO4]2 as a novel bis-imidazole-based acidic ionic liquid has been synthesized and characterized with a variety of techniques including FT-IR, 1H, 13C, 31/su

Engineering cellulose into water soluble poly(protic ionic liquid) electrolytes in the DBU/CO2/DMSO solvent system as an organocatalyst for the Knoevenagel condensation reaction

The facile design and preparation of polyelectrolytes is a frontier topic in the fields of polymer science, energy storage devices and catalysis. Herein, linear water soluble cellulosic poly(protic ionic liquid) (CPIL) electrolytes were facilely and atom economically prepared after the dissolution of cellulose in the newly developed DBU/CO2/DMSO solvent system, followed by the simple addition of succinic anhydride under mild conditions. The DBU not only participated in the dissolution of cellulose as a solvent component, but also acted as an organocatalyst for the acylation reaction of cellulose with succinic anhydride, as well as a cation component in the targeted CPIL electrolytes. The reaction was optimized, and the effect of the reaction conditions on the chemical and physical properties of the CPILs was investigated. And then, as a proof of concept, the CPIL electrolyte aqueous solution was successfully used as the catalytic reaction media for the Knoevenagel condensation reaction. It was found that the reaction was homogeneous at the beginning, and the products could precipitate out from the media with the proceeding of the reaction, thus affording satisfactory filtration yields ranging from 56.7% to 93.8%. The solution properties of the CPIL aqueous solution were primarily investigated towards an in-depth understanding of the catalytic mechanism, by which a synergetic catalytic mechanism of the CPILs was proposed, and the reaction started with a nucleophilic addition reaction, and was then followed by a fast dehydration reaction. Finally, the direct reusability potential of the CPIL aqueous solution after the product filtration was also primarily investigated for the Knoevenagel condensation reaction.

Knoevenagel condensation in aqueous media promoted by 2,2′-bipyridinium dihydrogen phosphate as a green efficient catalyst

A 2,2′-Bipyridine-based ionic compound named 2,2′-bipyridinium dihydrogen phosphate was synthesized by addition of phosphoric acid to a solution of 2,2′-Bipyridine in dichloromethane. After the characterization using FT-IR, mass, 1H, 13C and 31P NMR techniques, it was used as a Bronsted dicationic acidic catalyst for the promotion of the synthesis of 2-arylidene malononitrile and 5-arylidene barbituric acid derivatives via Knoevenagel condensation reaction in water. Some of the advantages of this method are the utilization of an easy preparable, cost-effective and eco-friendly organic salt as a catalyst within high rates and yields of the reactions, simple and quick work-up and acceptable reusability of the catalyst.

Introduction of succinimide as a green and sustainable organo-catalyst for the synthesis of arylidene malononitrile and tetrahydrobenzo[b] pyran derivatives

Aim and Objective: In this work, we tried to introduce a non-toxic and stable organic compound named succinimide as a green and efficient organo-catalyst for the promotion of the synthesis of arylidene malononitrile and tetrahydrobenzo[b]pyran derivatives

Hydroquinone and benzoquinone-catalyzed aqueous Knoevenagel condensation

A Knoevenagel condensation of various aldehydes with malononitrile effectively proceeded in the presence of hydroquinone/benzoquinone mixed catalysts at room temperature in H2O. Furthermore, γ-deuterium-labeled α,β-unsaturated nitrile derivatives were als

Amine-functionalized hollow mesoporous nano-bowl with bulky acid-imprinted free space around base sites and DMF-annealed mesoporous channels as an efficient solid base catalyst

Tailoring free spaces around catalytic sites and constructing inter-connected channels between them are highly attractive for achieving easy accessibility of reactants to catalytic sites. In this study, a strategy for constructing free space around base s