282734-63-8

Usage

Uses

Used in Medicinal Chemistry:
2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine is used as a chemical building block for the development of new pharmaceuticals. Its unique structure allows for further modifications and structure-activity relationship studies, contributing to the discovery of novel drugs with improved efficacy and selectivity.
Used in Drug Discovery:
2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine is used as a potential candidate in drug discovery due to its potential biological activities. Its synthesis and properties make it a valuable tool for exploring new therapeutic targets and developing innovative treatments for various diseases.
Used in Agrochemicals:
2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine is used as a building block for the development of new agrochemicals. Its unique structure and potential biological activities make it a promising candidate for the creation of novel pesticides, herbicides, or other agricultural chemicals to improve crop protection and yield.

InChI:InChI=1/C13H9IN2O2S/c14-12-9-10-5-4-8-15-13(10)16(12)19(17,18)11-6-2-1-3-7-11/h1-9H

Upstream product

• 143141-23-5 1-benzenesulfonyl-1H-pyrrolo[2,3-b]pyridine 
• 271-63-6 7-Azaindole 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 282734-70-7 methyl (E)-3-[(1-phenylsulfonyl)-1H-pyrrolo [2,3-b]-pyridin-2-yl]propenoate 
• 1227270-32-7 2-iodo-1H-pyrrolo[2,3-b]pyridine 
• 1485294-48-1 2-[1-(3-azidomethylbenzyl)-1H-[1,2,3]triazol-4-yl]-1H-pyrrolo[2,3-b]pyridine 
• 1485294-38-9 C₂₄H₂₆N₈ 
• 282734-73-0 methyl 9-phenylsulfonyl-5,6,7,8-tetrahydro-9H-pyrido[2,3-b]indole-5-carboxylate 
• 282734-64-9 1-phenylsulfonyl-2-vinyl-1H-pyrrolo[2,3-b]pyridine 

Relevant academic research and scientific papers

ESTROGEN RECEPTOR ANTAGONIST

Provided is an indole compound. In particular, disclosed are a compound represented by formula (II) or an isomer or pharmaceutically acceptable salt thereof and a use of the same as an estrogen receptor antagonist in preparing a drug for treating estrogen receptor-positive breast cancer.

Design and synthesis of azaindole heterocycle decorated new scaffold in fluorometric sensing of F? and H2PO4?

7-Azaindole has been used in designing new molecular structure 1 on enediyne spacer for its application in anion sensing. New structure 1 has been established as efficient fluorescent sensor of H2PO4? and F? ion

Synthesis, biological evaluation and molecular modeling of a novel series of 7-azaindole based tri-heterocyclic compounds as potent CDK2/Cyclin E inhibitors

From four molecules, inspired by the structural features of fascaplysin, with an interesting potential to inhibit cyclin-dependent kinases (CDKs), we designed a new series of tri-heterocyclic derivatives based on 1H-pyrrolo[2,3-b]pyridine (7-azaindole) an

Azaindole-1,2,3-triazole conjugate as selective fluorometric sensor for dihydrogenphosphate

A new receptor 1 has been designed and synthesized. The open cavity of 1 selectively recognizes H2PO4- over a series of other anions in CH3CN containing 0.01% DMSO by exhibiting a ratiometric change in emission.

A convenient iodination of indoles and derivatives

We report a direct iodination of indole and derivative compounds with iodine monochloride (ICl) in the presence of Celite. This procedure has now been extended to the iodination of substituted indoles, azaindoles and pyrroles. The scope of this procedure

Synthesis of pyrido[2,3-b]indole derivatives via Diels-Alder reactions of 2- and 3-vinylpyrrolo[2,3-b]pyridines

Diels-Alder reactions between 2- or 3-vinylpyrrolo[2,3-b]pyridine with various dienophiles were investigated. The pyrido[2,3-b]indole adducts 9 and 13 obtained led us to the preparation of potential cytotoxic agents 19 and 20. (C) 2000 Elsevier Science Lt