282735-66-4 Usage
General Description
(5R,6S)-5,6-Diphenyl-2-morpholinone is a chemical compound with the molecular formula C17H17NO2. It is a morpholinone derivative with a chiral center and two phenyl groups attached to the carbon at positions 5 and 6. (5R,6S)-5,6-Diphenyl-2-morpholinone is used as a starting material in the synthesis of pharmaceuticals and agrochemicals, and also serves as a key intermediate in the preparation of various bioactive molecules. It possesses biological activity and has been studied for its potential pharmacological properties. Additionally, (5R,6S)-5,6-Diphenyl-2-morpholinone is also utilized in chemical research and as a building block for the synthesis of diverse organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 282735-66-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,2,7,3 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 282735-66:
(8*2)+(7*8)+(6*2)+(5*7)+(4*3)+(3*5)+(2*6)+(1*6)=164
164 % 10 = 4
So 282735-66-4 is a valid CAS Registry Number.
InChI:InChI=1/C16H15NO2/c18-14-11-17-15(12-7-3-1-4-8-12)16(19-14)13-9-5-2-6-10-13/h1-10,15-17H,11H2/t15-,16+/m1/s1
282735-66-4Relevant articles and documents
Diastereoselective intermolecular radical addition to nitrones
Ueda, Masafumi,Miyabe, Hideto,Teramachi, Masako,Miyata, Okiko,Naito, Takeaki
, p. 6653 - 6660 (2007/10/03)
The intermolecular radical addition to chiral nitrones 2, 4, 5, and 16 was studied. The isopropyl radical addition to Oppolzer's camphorsultam derivative 2 of glyoxylic nitrone proceeded with excellent diastereoselectivity to give the desired isopropylated product 3a accompanied by the diisopropylated product 3b. A high degree of stereocontrol in the reaction of cyclic nitrone 4 was achieved. The ethyl radical addition to nitrone 4 with triethylborane afforded the desired ethylated product 9a accompanied by the diethylated product 10a and the ethylated nitrone 11a. To evaluate the utility of cyclic nitrone 4, several alkyl radicals were employed in the addition reaction, which afforded the alkylated products 9b-d with excellent diastereoselectivities. In the presence of Mg(ClCO4)2, the ethyl radical addition to BIGN 16 afforded selectively syn isomers. In contrast, the alkyl radical addition to 16 took place even in the absence of Lewis acid to give anti isomers.