282735-67-5Relevant academic research and scientific papers
Asymmetric, stereocontrolled total synthesis of (+) and (-)-spirotryprostatin B via a diastereoselective azomethine ylide [1,3]-dipolar cycloaddition reaction
Sebahar, Paul R,Osada, Hiroyuki,Usui, Takeo,Williams, Robert M
, p. 6311 - 6322 (2007/10/03)
The asymmetric, stereocontrolled total syntheses of (+) and (-)-spirotryprostatin B (2) are described. Formation of the core pyrrolidine ring was accomplished via a diastereoselective asymmetric [1,3]-dipolar cycloaddition reaction. Addition of 3-methoxy-
The synthesis of spirooxindole pyrrolidines via an asymmetric azomethine ylide [1,3]-dipolar cycloaddition reaction
Sebahar, Paul R.,Williams, Robert M.
, p. 563 - 575 (2007/10/03)
The asymmetric [1,3] dipolar cycloaddition reactions of azomethine ylides derived from 5,6-diphenylmorpholin-2-one with various aldehydes and ethyl oxindolylideneacetate are described. Addition of an aldehyde to the morpholin-2-one, under essentially neut
