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BETA-ELEMONIC ACID is a triterpene compound derived from Boswellia (Burseraceae) that has been found to exhibit significant anticancer activity. It is characterized by its ability to inhibit the growth of non-small cell lung cancer (NSCLC) A549 cells in vitro, induce apoptosis and cytotoxicity in a dose-dependent manner, and modulate various cellular processes such as the production of reactive oxygen species (ROS) and COX-2 expression. Additionally, BETA-ELEMONIC ACID is a Pin1 inhibitor and is also used as a flavoring agent in the food industry.

28282-25-9

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28282-25-9 Usage

Uses

Used in Anticancer Applications:
BETA-ELEMONIC ACID is used as an anticancer agent for its ability to inhibit cell proliferation in human lung adenocarcinoma A549 cells. It targets the MAPK signaling pathway, activates ROS, and depletes glutathione, leading to the suppression of tumor growth and progression.
Used in Drug Delivery Systems:
Although not explicitly mentioned in the provided materials, BETA-ELEMONIC ACID's potential as a pharmaceutical candidate may lead to the development of novel drug delivery systems to enhance its applications and efficacy against cancer cells.
Used in Flavoring Agents:
BETA-ELEMONIC ACID is used as a flavoring agent in the food industry, taking advantage of its natural presence in herbs and spices, as well as its constituent role in elemi resin.
Used in Pharmaceutical Industry:
BETA-ELEMONIC ACID is used as a Pin1 inhibitor for its potential therapeutic applications in the pharmaceutical industry, targeting the inhibition of prolyl endopeptidase (IC50 = 39.74 μM) in vitro.

Check Digit Verification of cas no

The CAS Registry Mumber 28282-25-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,2,8 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 28282-25:
(7*2)+(6*8)+(5*2)+(4*8)+(3*2)+(2*2)+(1*5)=119
119 % 10 = 9
So 28282-25-9 is a valid CAS Registry Number.

28282-25-9 Well-known Company Product Price

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  • Sigma-Aldrich

  • (00708)  β-Elemonic acid  analytical standard

  • 28282-25-9

  • 00708-5MG

  • 4,661.28CNY

  • Detail

28282-25-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name β-Elemonic acid

1.2 Other means of identification

Product number -
Other names (2S)-6-methyl-2-[(10S,14S,17S)-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,7,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]hept-5-enoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:28282-25-9 SDS

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