28283-98-9 Usage
Uses
Used in Pharmaceutical and Agrochemical Industries:
2,3-Dioxoindoline-5-carboxamide is utilized as a key building block for the synthesis of various pharmaceuticals and agrochemicals. Its unique structure and reactivity contribute to the development of new compounds with therapeutic and pesticidal properties, respectively.
Used in Medicinal Chemistry Research:
As a drug candidate, 2,3-Dioxoindoline-5-carboxamide is employed in the research and development of treatments for a range of diseases, including cancer and infectious diseases. Its biological activity makes it a promising candidate for further investigation and potential clinical applications.
Used in Coordination Chemistry:
2,3-Dioxoindoline-5-carboxamide serves as a ligand in coordination chemistry, where it forms complexes with metal ions. These complexes can exhibit unique properties and applications, such as in catalysis or as functional materials.
Used in Organic Synthesis as a Reagent:
In chemical reactions, 2,3-Dioxoindoline-5-carboxamide acts as a reagent for the synthesis of complex organic molecules. Its ability to participate in various types of chemical transformations makes it a valuable tool in the synthesis of intricate organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 28283-98-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,2,8 and 3 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 28283-98:
(7*2)+(6*8)+(5*2)+(4*8)+(3*3)+(2*9)+(1*8)=139
139 % 10 = 9
So 28283-98-9 is a valid CAS Registry Number.
28283-98-9Relevant academic research and scientific papers
Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds
Liu, Pei,Liu, Hongbo,Sun, Qi,Liang, Hao,Li, Chunmei,Deng, Xiaobing,Liu, Ying,Lai, Luhua
, (2020/08/14)
SARS-CoV-2 3C-like protease is the main protease of SARS-CoV-2 and has been considered as one of the key targets for drug discovery against COVID-19. We identified several N-substituted isatin compounds as potent SARS-CoV-2 3C-like protease inhibitors. Th
Isatin compounds as noncovalent SARS coronavirus 3C-like protease inhibitors
Zhou, Lu,Liu, Ying,Zhang, Weilin,Wei, Ping,Huang, Changkang,Pei, Jianfeng,Yuan, Yaxia,Lai, Luhua
, p. 3440 - 3443 (2007/10/03)
A series of isatin derivatives were synthesized and tested against SARS CoV 3C-like protease. Substitutions at the N-1 and C-5 positions were examined to elucidate the differences in substrate binding sites of the rhinovirus 3C protease and SARS CoV 3C-li