28286-03-5

Basic information

• Product Name: Piperidine, 1-methyl-4-(4-nitrophenyl)-
• CAS NO: 28286-03-5
• Molecular Formula: C12H16N2O2
• Molecular Weight: 220.271
• Mol File: 28286-03-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Piperidine, 1-methyl-4-(4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 1-methyl-4-(4-nitrophenyl)-(28286-03-5)
• EPA Substance Registry System: Piperidine, 1-methyl-4-(4-nitrophenyl)-(28286-03-5)

Safety Data

• Hazardous Substances Data: 28286-03-5(Hazardous Substances Data)

Upstream product

• 771-99-3 4-phenylpiperidine 
• 50-00-0 formaldehyd 
• 883194-93-2 4-(4-nitro-phenyl)-piperidine hydrochloride 
• 26905-03-3 4-(4-Nitrophenyl)piperidine 
• 774-52-7 1-methyl-4-phenylpiperidine 

Downstream Products

• 454482-12-3 4-(1-methyl-4-piperidyl)-phenylamine 

Relevant articles and documents

PI3 KINASES

The invention relates to the novel compounds of formula (1), which, due to their pharmaceutical effect as PI3 kinase modulators, are suitable for use in the therapy and treatment of inflammatory or allergic diseases. Examples of these diseases are inflammatory and allergic respiratory diseases, inflammatory diseases of the gastro-intestinal system and of the locomotor apparatus, inflammatory and allergic skin diseases, inflammatory ophthalmic diseases, diseases of the nasal mucosa, inflammatory or allergic autoimmune reactive conditions, or renal inflammations.

2-AMINOPYRIMIDINE AND 2-AMINOPYRIDINE-4-CARBAMATES FOR USE IN THE TREATMENT OF AUTOIMMUNE DISEASES

The present invention relates to pyrimidine or pyridine carbamate compounds having the general Formula (1) and pharmaceutically acceptable salts or derivatives thereof. Also included are methods of treatment of various diseases and conditions, including inflammation, inhibition of T cell activation and proliferation, arthritis, organ transplant, ischemic or reperfusion injury, myocardial infarction, stroke, multiple sclerosis, inflammatory bowel disease, Crohn's disease, lupus, hypersensitivity, type 1 diabetes, psoriasis, dermatitis, Hashimoto's thyroiditis, Sjogren's syndrome, autoimmune hyperthyroidism, Addison's disease, autoimmune diseases, glomerulonephritis, allergic diseases, asthma, hayfever, eczema, cancer, colon carcinoma, thymoma, just to name a few, in a mammal, the methods comprising administering a therapeutically-effective amount a compound of Formula I, or a salt or derivative form thereof, as described above.

SUBSTITUTED ALKYLAMINE DERIVATIVES AND METHODS OF USE

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