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28290-41-7

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28290-41-7 Usage

Chemical Properties

Brown Oil

Uses

Different sources of media describe the Uses of 28290-41-7 differently. You can refer to the following data:
1. An analog of Farnesol, produced in the dimorphic fungus Candida albicans
2. Farnesyl bromide was used in the preparation of:S-trans, trans-farnesyl-L-cysteine methylester, a post translational modified amino acidumbelliprenin, starting reagent for the synthesis of (±)-farnesiferol A and (±)-farnesiferol Cprenylated peptides

Check Digit Verification of cas no

The CAS Registry Mumber 28290-41-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,2,9 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 28290-41:
(7*2)+(6*8)+(5*2)+(4*9)+(3*0)+(2*4)+(1*1)=117
117 % 10 = 7
So 28290-41-7 is a valid CAS Registry Number.
InChI:InChI=1/C15H25Br/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16/h7,9,11H,5-6,8,10,12H2,1-4H3/b14-9+,15-11+

28290-41-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (E,E)-Farnesyl Bromide

1.2 Other means of identification

Product number -
Other names 1-bromo-3,7,11-trimethyldodeca-2,6,10-triene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:28290-41-7 SDS

28290-41-7Relevant articles and documents

Regiospecific Synthesis of Calcium-Independent Daptomycin Antibiotics using a Chemoenzymatic Method

Mupparapu, Nagaraju,Lin, Yu-Hsin Cindy,Kim, Tae Ho,Elshahawi, Sherif I.

, p. 4176 - 4182 (2021/02/01)

Daptomycin (DAP) is a calcium (Ca2+)-dependent FDA-approved antibiotic drug for the treatment of Gram-positive infections. It possesses a complex pharmacophore hampering derivatization and/or synthesis of analogues. To mimic the Ca2+-binding effect, we used a chemoenzymatic approach to modify the tryptophan (Trp) residue of DAP and synthesize kinetically characterized and structurally elucidated regiospecific Trp-modified DAP analogues. We demonstrated that the modified DAPs are several times more active than the parent molecule against antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria. Strikingly, and in contrast to the parent molecule, the DAP derivatives do not rely on calcium or any additional elements for activity.

ANTIBIOTIC COMPOUNDS

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Paragraph 00117, (2021/04/02)

Provided herein are lipidated glycopeptide compounds of formula (I); or a pharmaceutically acceptable salt, stereoisomer, solvate, or prodrug thereof. R1 is a lipid, R2 is -H or a lipid, and R3 and R4 are as defined herein. These compounds have antibiotic activity. Also provided are formulations comprising such compounds; as well as such compounds or formulations for use as a medicament. The compounds and formulations may also be used in the treatment of bacterial infection.

Protein degradation targeting chimeric compound, preparation method and medical application thereof

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Paragraph 0218-0219; 0222-0223, (2021/03/31)

The invention relates to a protein degradation targeting chimeric compound, a preparation method and medical application thereof, specifically to a compound as shown in a general formula (I), a preparation method of the compound, and application of the co

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