28291-75-0

Basic information

• Product Name: N-Cyclohexylbenzothiazole-2-amine
• Synonyms: N-Cyclohexyl-2-benzothiazolamine;N-Cyclohexylbenzothiazole-2-amine
• CAS NO: 28291-75-0
• Molecular Formula: C₁₃H₁₆N₂S
• Molecular Weight: 232.34
• Mol File: 28291-75-0.mol

Chemical Properties

• Melting Point: 107 °C
• Boiling Point: 368.0±25.0 °C(Predicted)
• Appearance: /
• Density: 1.234±0.06 g/cm3(Predicted)
• PKA: 3.44±0.10(Predicted)
• CAS DataBase Reference: N-Cyclohexylbenzothiazole-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Cyclohexylbenzothiazole-2-amine(28291-75-0)
• EPA Substance Registry System: N-Cyclohexylbenzothiazole-2-amine(28291-75-0)

Safety Data

• Hazardous Substances Data: 28291-75-0(Hazardous Substances Data)

Usage

Uses

Used in Rubber and Latex Industry:
N-Cyclohexylbenzothiazole-2-amine is used as an accelerator for the vulcanization process in the production of rubber and latex. It facilitates the cross-linking of polymer chains, which is essential for improving the physical properties of rubber, such as its elasticity, strength, and durability. The use of CBS ensures the production of high-quality rubber products that meet the demands of various applications.
As a potential carcinogen, CBS requires careful handling and adherence to safety protocols to minimize health risks for workers and the environment. This includes proper storage, usage guidelines, and disposal methods to ensure the safe and effective application of this chemical compound in the rubber and latex industry.

Upstream product

• 722-03-2 N-cyclohexyl-N'-phenylthiourea 
• 1418139-86-2 C₁₃H₁₅IN₂ 
• 615-20-3 2-chlorobenzo[d][1,3]thiazole 
• 108-91-8 cyclohexylamine 
• 931-53-3 Cyclohexyl isocyanide 
• 137-07-5 2-amino-benzenethiol 
• 98041-44-2 2-iodophenyl isothiocyanate 
• 250122-02-2 C₁₃H₁₇IN₂S 
• 615-43-0 2-iodophenylamine 
• 1122-82-3 isothiocyanatocyclohexane 
• 4426-69-1 cyclohexyl isoselenocyanate 
• 250122-00-0 C₁₃H₁₇BrN₂S 

Downstream Products

• 137267-11-9 1-{2-[(Z)-Cyclohexylimino]-benzothiazol-3-yl}-3-phenoxy-propan-2-ol 
• 120-78-5 di(benzothiazol-2-yl)disulfide 
• 108-91-8 cyclohexylamine 

Relevant articles and documents

Molecular iodine-mediated synthesis of thiocarbamates from thiols, isocyanides and water under metal-free conditions

A simple and practical molecular iodine-mediated method for the efficient construction of thiocarbamates from isocyanides, thiols and water under metal-free and mild conditions has been developed. A variety of thiocarbamates were easily synthesized through this methodology, which has the advantages of simple operation, eco-friendly conditions, good functional group tolerance, and readily accessible raw materials.

Iodine-catalyzed formation of substituted 2-aminobenzothiazole derivatives in PEG400

An iodine-catalyzed formation of substituted 2-aminobenzothiazole derivatives is herein described using hydrogen peroxide as an oxidant in PEG400. The method enabled an efficient environmentally sound access to this valuable scaffold in moderate to excellent yields under metal-free conditions.

A practical synthesis of 2-aminobenzothiazoles via copper(I)-catalyzed tandem reaction of 2-iodoanilines with isothiocyanates in ionic liquids

A copper(I)-catalyzed tandem reaction of 2-iodoanilines with isothiocyanates was achieved in hydrophobic [bmim][PF6] ionic liquid under mild conditions, generating a variety of 2-aminobenzothiazoles in good to excellent yields. The tandem reaction that was carried out in [bmim][PF6] has some obvious advantages such as accelerated reaction rate and increased yield as compared with the reaction run in volatile solvents such as toluene. Furthermore, the CuI/1,10-phenanthroline catalytic system can be reused up to eight times without loss of activity and efficiency.

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N-Substituted 2-amino-1,3-benzothiazoles and 2,3-disubstituted indoles were prepared by C-S and C-C cross-coupling reactions of 2-iodoanilines with isothiocyanates or 1,3-dicarbonyl compounds, respectively, in the presence of magnetic nanoparticles functionalized with a copper(II)-Schiff base complex as an efficient and reusable catalyst.

Water-Mediated Synthesis of Benzazole and Thiourea Motifs by Reacting Naturally Occurring Isothiocyanate with Amines

An efficient, green, and facile method has been developed for the synthesis of benzazole and thiourea analogues from naturally occurring erucin in moderate to good yields. The reaction was carried out in water without using any metal catalyst or base. The present method tolerated the various functional groups on aromatic rings and also applicable for other isothiocyanates.

Copper-catalyzed synthesis of 2-aminobenzothiazoles from carbodiimide and sodium hydrosulfide

An efficient copper-catalyzed method for the synthesis of a variety of 2-aminobenzothiazoles has been developed. The reaction proceeded from carbodiimide and sodium hydrosulfide via a tandem reaction in the presence of copper(ii) trifluoromethanesulfonate to afford the corresponding 2-aminobenzothiazole derivatives in good to perfect yields. This journal is the Partner Organisations 2014.

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