28300-74-5

Basic information

• Product Name: Potassium antimonyl tartrate sesquihydrate
• Synonyms: POTASSIUM ANTIMONY TARTRATE TRIHYDRATE;TARTAR EMETIC TRIHYDRATE;antimonate(2)-,bis(mu-tartrato(4-))di-,dipotassium,trihydrate;Antimonate(2)-,bis[μ-tartrato(4-)]di-,dipotassium,trihydrate;emetique;emetique(french);Ent50,434;epapesticidechemicalcode006201
• CAS NO: 28300-74-5
• Molecular Formula: C8H10K2O15Sb2
• Molecular Weight: 667.87
• EINECS: 234-293-3
• Product Categories: Industrial/Fine Chemicals;Organometallics
• Mol File: 28300-74-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: ≥300 °C(lit.)
• Appearance: White/Powder
• Density: 2,607 g/cm3
• Storage Temp.: Storage temperature: no restrictions.
• Solubility: water: soluble
• Water Solubility: 8.3 g/100 mL
• Stability: Stable. Incompatible with alkalies, carbonates, strong oxidizing agents.
• Merck: 14,700
• CAS DataBase Reference: Potassium antimonyl tartrate sesquihydrate(CAS DataBase Reference)
• NIST Chemistry Reference: Potassium antimonyl tartrate sesquihydrate(28300-74-5)
• EPA Substance Registry System: Potassium antimonyl tartrate sesquihydrate(28300-74-5)

Safety Data

• Hazard Codes: Xn,N
• Statements: 20/22-51/53
• Safety Statements: 61
• RIDADR: UN 1551 6.1/PG 3
• WGK Germany: 3
• RTECS: CC6825000
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 28300-74-5(Hazardous Substances Data)

Usage

Chemical Properties

Different sources of media describe the Chemical Properties of 28300-74-5 differently. You can refer to the following data:
1. colourless crystals
2. Antimony potassium tartrate is an odorless, colorless, crystalline material or white powder with a sweetish, metallic taste.

Uses

Different sources of media describe the Uses of 28300-74-5 differently. You can refer to the following data:
1. As mordant in the textile and leather industry.
2. Potassium antimonyl tartrate trihydrate is used in chemical therapy treatment of Leishmania guyanensis and Leishmania braziliensis however may be susceptible to antimony resistance.
3. Potassium antimonyl tartrate trihydrate was employed as an Sb(III)-containing drug to investigate its ability to induce cell death associated with DNA fragmentation in axenic amastigotes of Leishmania infantum?It may also be used as a standard solution to determine the metalloid concentration such as Sb(III) and Sb(V) in surface soil, using high performance liquid chromatography coupled to inductively coupled plasma-mass spectrometry (HPLC-ICP-MS).

General Description

Potassium antimonyl tartrate sesquihydrate solid is a colorless crystalline solid or a white powder. Potassium antimonyl tartrate sesquihydrate is soluble in water. Potassium antimonyl tartrate sesquihydrate is used in textile and leather processing and as an insecticide.

Air & Water Reactions

Potassium antimonyl tartrate sesquihydrate effloresces on exposure to air. Water soluble.

Reactivity Profile

Potassium antimonyl tartrate sesquihydrate reacts with tannic acid, alkalis and their carbonates, lead salts, astringent infusions (cinchona, rhubarb, etc.), acacia, antipyrene and mercury bichloride. Potassium antimonyl tartrate sesquihydrate also reacts with acids, salts of heavy metals, albumins, soap and tannins. Potassium antimonyl tartrate sesquihydrate can react with strong oxidizing agents. .

Health Hazard

Inhalation causes inflammation of membranes of nose and throat, upper respiratory irritation, headache, dizziness. Ingestion causes gastrointestinal upset, strong irritation, vomiting. Contact with eyes or skin causes irritation. Further symptoms of exposure include nervous complaints (i.e., irritability, dizziness, muscular and neurological pain).

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways.

Safety Profile

Human poison by intravenous route, producing liver and kidney changes, somnolence, dyspnea, and pupillary dilation. Poison by ingestion, subcutaneous, intravenous, intramuscular, and intraperitoneal routes. Large doses cause severe liver damage. Human mutation data reported. Used medicinally, the therapeutic dose is close to the toxic dose. Upon decomposition it emits toxic fumes of K2O and Sb.

Potential Exposure

It is used in medicine; textile and leather dyeing; as an insecticide.

Shipping

UN1549 Antimony potassium tartrate, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Purification Methods

Crystallise it from water (3mL/g) between 100o and 0o. Dry it at 100o. [Chinoporos & Papathanosopolos J Phys Chem 65 1643 1961, Beilstein 3 III 1014, 3 IV 1227.]

Incompatibilities

Solution will react with alkaline materials.

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.

InChI:InChI=1/2C4H4O6.2K.H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;1H2;;/q2*-2;2*+1;;2*+3/p-4/rC8H6O12Sb2.2K.H2O/c9-5(10)1-3-7(13)19-22(17-3)16-2(6(11)12)4-8(14)20-21(15-1)18-4;;;/h1-4H,(H,9,10)(H,11,12);;;1H2/q;2*+1;/p-2