2831-90-5

Basic information

• Product Name: 3-hydroxy-2,2-bis(hydroxymethyl)propanoic acid
• Synonyms: propanoic acid, 3-hydroxy-2,2-bis(hydroxymethyl)-
• CAS NO: 2831-90-5
• Molecular Formula: C₅H₁₀O₅
• Molecular Weight: 150.1299
• Mol File: 2831-90-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 488.1°C at 760 mmHg
• Flash Point: 263.1°C
• Density: 1.527g/cm³
• Vapor Pressure: 1.42E-11mmHg at 25°C
• Refractive Index: 1.55
• CAS DataBase Reference: 3-hydroxy-2,2-bis(hydroxymethyl)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-2,2-bis(hydroxymethyl)propanoic acid(2831-90-5)
• EPA Substance Registry System: 3-hydroxy-2,2-bis(hydroxymethyl)propanoic acid(2831-90-5)

Safety Data

• Hazardous Substances Data: 2831-90-5(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 75-07-0 acetaldehyde 
• 1522-92-5 2,2-bis(bromomethyl)-3-bromo-propan-1-ol 
• 3296-90-0 bis(bromomethyl)bis(hydroxymethyl)methane 
• 13103-49-6 acetic acid-(3-chloro-2,2-bis-chloromethyl-propyl ester) 
• 813-99-0 3-chloro-(2,2-chloromethyl)propan-1-ol 
• 115-77-5 Pentaerythritol 
• 7732-18-5 water 
• 52813-48-6 3-bromo-2,2-bis(bromomethyl)propanoic acid 
• 17831-70-8 3-chloro-2,2-bis(chloromethyl)propionic acid-1 

Downstream Products

• 101782-65-4 3-acetoxy-2,2-bis-acetoxymethyl-propionic acid p-toluidide 

Relevant articles and documents

NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PHARMACEUTICAL APPLICATION THEREOF

It is intended to provide a compound represented by the general formula (I): (I) (wherein all the symbols are as defined in the description) which has a p38 MAP kinase inhibitory activity, a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof. The compound of the invention is useful for preventing or treating a disease in which the abnormal production of a cytokine such as an inflammatory cytokine or a chemokine or overreaction to them is considered to be involved in the cause and aggravation of pathological conditions, in other words, an inflammatory disease, a respiratory disease, a cardiovascular disease, a central nervous system disease or the like, which is a cytokine-mediated disease.

Derivatives of Pentaerythritol, IV. - Identification of By-products in Pentaerythritol Process Liquors

Several previously unknown by-products of the pentaerythritol synthesis were identified by comparison of their GC/MS spectra with the spectra of pure compounds.Furthermore, pure 2-hydroxymethyl-2-(methoxymethoxymethyl)-1,3-propandiol (5) was isolated from mother liquors, and the reference compounds 5-hydroxymethyl-1,3-dioxane-5-carboxylic acid (6) and 3--2,2-bis(hydroxymethyl)propanoic acid (7) were synthesized.