2831-90-5

Upstream product

• 1522-92-5 2,2-bis(bromomethyl)-3-bromo-propan-1-ol 
• 3296-90-0 bis(bromomethyl)bis(hydroxymethyl)methane 
• 13103-49-6 acetic acid-(3-chloro-2,2-bis-chloromethyl-propyl ester) 
• 813-99-0 3-chloro-(2,2-chloromethyl)propan-1-ol 
• 115-77-5 Pentaerythritol 
• 7732-18-5 water 
• 50-00-0 formaldehyd 
• 75-07-0 acetaldehyde 
• 52813-48-6 3-bromo-2,2-bis(bromomethyl)propanoic acid 
• 17831-70-8 3-chloro-2,2-bis(chloromethyl)propionic acid-1 

Downstream Products

• 101782-65-4 3-acetoxy-2,2-bis-acetoxymethyl-propionic acid p-toluidide 

Relevant academic research and scientific papers

NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PHARMACEUTICAL APPLICATION THEREOF

It is intended to provide a compound represented by the general formula (I): (I) (wherein all the symbols are as defined in the description) which has a p38 MAP kinase inhibitory activity, a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof. The compound of the invention is useful for preventing or treating a disease in which the abnormal production of a cytokine such as an inflammatory cytokine or a chemokine or overreaction to them is considered to be involved in the cause and aggravation of pathological conditions, in other words, an inflammatory disease, a respiratory disease, a cardiovascular disease, a central nervous system disease or the like, which is a cytokine-mediated disease.

Cosmetic or dermatological topical compositions comprising dendritic polyesters

The present invention relates to cosmetic or dermatological compositions capable of being applied to the skin, the keratinous fibers, the nails, the semimucous membranes and/or the mucous membranes, and which includes a dendritic polyester polymer having terminal hydroxyl functional groups or the combination of such a polymer with a film-forming polymer. It also relates to methods of cosmetic or dermatological treatment using these compositions as well as the use of the compositions for the preparation of dermatological or cosmetic compositions.

Derivatives of Pentaerythritol, IV. - Identification of By-products in Pentaerythritol Process Liquors

Several previously unknown by-products of the pentaerythritol synthesis were identified by comparison of their GC/MS spectra with the spectra of pure compounds.Furthermore, pure 2-hydroxymethyl-2-(methoxymethoxymethyl)-1,3-propandiol (5) was isolated from mother liquors, and the reference compounds 5-hydroxymethyl-1,3-dioxane-5-carboxylic acid (6) and 3--2,2-bis(hydroxymethyl)propanoic acid (7) were synthesized.