28333-02-0Relevant academic research and scientific papers
Cloning and structure-function analyses of quinolone- and acridone-producing novel type III polyketide synthases from citrus microcarpa
Mori, Takahiro,Shimokawa, Yoshihiko,Matsui, Takashi,Kinjo, Keishi,Kato, Ryohei,Noguchi, Hiroshi,Sugio, Shigetoshi,Morita, Hiroyuki,Abe, Ikuro
, p. 28845 - 28858 (2013/10/22)
Background:Type III polyketide synthases (PKSs) synthesize various polyketide and alkaloid scaffolds. Results:QNS synthesizes quinolone as the single product, whereas ACS produces acridone as the major product. Conclusion:QNS and ACS are novel quinolone- and acridone-producing type III PKSs, respectively. Significance:Structure-function analyses of QNS and ACS provide insights into molecular bases for alkaloid biosyntheses.
New acridone derivatives obtained by heating the HCl salt of acronycine
Funayama, Shinji,Pan, Tzu-Yun,Nozoe, Shigeo,Cordell, Geoffrey A.
, p. 1251 - 1256 (2007/10/03)
By heating the HCl salt of acronycine (1), the new acridone derivatives (6, 9, 13 and 15) were obtained together with noracronycine (2), dihydronoracronycine (3), 1,3-dihydroxy-10-methylacridone (4) and (5). Compound (5), one of the main products of this reaction, is a linear type dihydro derivative of 2, compound (9) is a furanoacridone derivative with a geminal methyl group and compound (15) is a derivative of 5 with an additional C5 unit.
