13161-83-6

Basic information

• Product Name: 1-Hydroxy-3-methoxy-N-methylrutacridone
• Synonyms: 1-Hydroxy-3-methoxy-10-methylacridin-9(10H)-one;1-Hydroxy-3-methoxy-N-methylrutacridone;1-hydroxy-3-methoxy-10-methyl-9(10H)-acridinone
• CAS NO: 13161-83-6
• Molecular Formula: C₁₅H₁₃NO₃
• Molecular Weight: 255.2686
• Mol File: 13161-83-6.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 465°Cat760mmHg
• Flash Point: 235°C
• Appearance: /
• Density: 1.302g/cm³
• Vapor Pressure: 2.87E-09mmHg at 25°C
• Refractive Index: 1.641
• CAS DataBase Reference: 1-Hydroxy-3-methoxy-N-methylrutacridone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Hydroxy-3-methoxy-N-methylrutacridone(13161-83-6)
• EPA Substance Registry System: 1-Hydroxy-3-methoxy-N-methylrutacridone(13161-83-6)

Safety Data

• Hazardous Substances Data: 13161-83-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H13NO3/c1-16-12-6-4-3-5-10(12)15(18)11-7-9(19-2)8-13(17)14(11)16/h3-8,17H,1-2H3

Upstream product

• 13146-23-1 copper(I) phenylacetylenide 
• 88901-72-8 1-Hydroxy-2-iodo-3-methoxy-10-methyl-9-acridone 
• 115-18-4 2-methyl-3-buten-2-ol 
• 88901-73-9 1,3-Dihydroxy-2-iodo-10-methyl-9-acridone 
• 20324-10-1 1,3-dihydroxyacridin-9(10H)-one 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 
• 108-73-6 3,5-dihydroxyphenol 
• 82354-37-8 3-O-methylglycocitrine-II 
• 56964-06-8 (3-methyl-3-buten-1-yn-1-yl)copper 
• 28333-02-0 N-methyl-1,3-dihydroxyacridone 

Downstream Products

• 13082-10-5 1,3-dimethoxy-N-methylacridone 
• 171919-98-5 N-<2-(3-methoxy-10-methyl-1-oxo-1,10-dihydroacridin-9-yl)phenyl>-2,2-dimethylpropionamide 
• 171919-96-3 tert-butyl 4-methoxy-2-(3-methoxy-10-methyl-1-oxo-1,10-dihydroacridin-9-yl)phenylcarbamate 
• 1027644-70-7 N-[2-(3-methoxy-10-methyl-9-oxo-9,10-dihydro-acridin-1-yl)-phenyl]-2,2-dimethyl-propionamide 

Relevant articles and documents

Easy access to pyranoacridines, pyranoxanthenes, and arylchromenes through a domino reaction

A series of pyrano[2,3,4-kl]acridines has been synthesized through an unprecedented domino reaction involving1-hydroxy-3-methoxy-10-methylacridone and Grignard reagents. This method has been successfully applied to xanthone, anthracenone, and benzophenone

Antitumour polycyclic acridines. Palladium(0) mediated syntheses of quino[4,3,2-kl]acridines bearing peripheral substituents as potential telomere maintenance inhibitors

Pd(0) mediated couplings between substituted 2-(pivaloylamino)benzeneboronic acids and 3,6-disubstituted-10-methylacridones 13 bearing a bromo or trifluoromethylsulfonyloxy substituent in the 1-position yield intermediate 1-arylacridones 16 which can be c

Natural Product Chemistry, 143 Convenient Synthesis of Isoacronycine and Some Other New Acridone Derivatives

The iodination of 1,3-dihydroxy-9-acridone (1), 1-hydroxy-3-methoxy-10-methyl-9-acridone (2) and 1,3-dihydroxy-10-methyl-9-acridone (3) yields 1,3-dihydroxy-2,4-diiodo-9-acridone (4), 1-hydroxy-2-iodo-3-methoxy-10-methyl-9-acridone (5) and 1,3-dihydroxy-2-iodo-10-methyl-9-acridone (6), respectively.The methylation of 4 and 5 gives 2,4-diiodo-1,3-dimethoxy-10-methyl-9-acridone (7) and 2-iodo-1,3-dimethoxy-10-methyl-9-acridone (9), respectively.The direct C-C coupling of 2-methyl-3-buten-2-ol to the compounds 5, 7 and 9 by palladium catalysed Heck condensation method gives three new acridone derivatives 1-hydroxy-2-(3-hydroxy-3-methyl-1-butenyl)-3-methoxy-10-methyl-9-acridone (10), 2,4-bis(3-hydroxy-3-methyl-1-butenyl)-1,3-dimethoxy-10-methyl-9-acridone (12) and 2-(3-hydroxy-3-methyl-1-butenyl)-1,3-dimethoxy-10-methyl-9-acridone (13) while compound 6 is converted into isonoracronycine (11).The methylation of 11 yields isoacronycine (14). Key words: Acridone alkaloids / Heck condensation / Isonoracronycine / Isoacronycine