2834-84-6

Basic information

• Product Name: carbazamidine sulphate
• Synonyms: carbazamidine sulphate;GUANIDINE,1-AMINO-,HYDROGENSULPHATE
• CAS NO: 2834-84-6
• Molecular Formula: CH₆N₄*H₂O₄S
• Molecular Weight: 172.16362
• EINECS: 220-605-5
• Mol File: 2834-84-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 261.4°Cat760mmHg
• Flash Point: 111.9°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.015-0.018Pa at 20-25℃
• CAS DataBase Reference: carbazamidine sulphate(CAS DataBase Reference)
• NIST Chemistry Reference: carbazamidine sulphate(2834-84-6)
• EPA Substance Registry System: carbazamidine sulphate(2834-84-6)

Safety Data

• Hazardous Substances Data: 2834-84-6(Hazardous Substances Data)

Usage

General Description

Carbazamidine sulphate is a chemical compound that acts as an inhibitor of nitric oxide synthase, which is an enzyme responsible for the production of nitric oxide in the body. carbazamidine sulphate has been studied for its potential use in the treatment of conditions such as septic shock, where the overproduction of nitric oxide can lead to vascular dysfunction and multiple organ failure. Carbazamidine sulphate has also been investigated for its potential use in the treatment of various other inflammatory and immunological conditions, due to its ability to modulate the production of nitric oxide. However, further research is needed to fully understand the potential therapeutic uses of this compound.

InChI:InChI=1/CH6N4.H2O4S/c2-1(3)5-4;1-5(2,3)4/h4H2,(H4,2,3,5);(H2,1,2,3,4)

Upstream product

• 2582-30-1 aminoguanidine bicarbonate 

Downstream Products

• 869-17-0 Trifluormethylglyoxal-bis-guanylhydrazon 
• 98087-86-6 5-(2-Methyl-pyridin-4-yl)-2H-[1,2,4]triazol-3-ylamine 
• 83417-23-6 3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine 
• 3663-61-4 5-(furan-2-yl)-2H-1,2,4-triazol-3-amine 
• 35607-27-3 5-(pyridin-3-yl)-2H-1,2,4-triazol-3-amine 
• 105445-19-0 5-(methoxymethyl)-4H-1,2,4-triazol-3-amine 
• 64107-26-2 N-[2-(Prop-2'-Ynoxy)-5-Bromo-Benzylidene]-N'-Amidino-Hydrazine 
• 64107-24-0 N-(o-cyclopropylbenzylidene)-N'-amidino-hydrazine 
• 136424-03-8 (E)-4-<2-<3-<<(aminoiminomethyl)hydrazono>ethoxy>-2-pyridinyl>ethenyl>benzoic acid sulphate 
• 136424-01-6 (E)-<2-<2-(4-tolyl)ethenyl>-3-pyridinyloxy>acetaldehyde guanylhydrazone sulphate 
• 136423-99-9 (E)-<2-(2-phenylethenyl)-3-pyridinyloxy>acetaldehyde guanylhydrazone sulphate 
• 136423-97-7 4-<<2-<<(aminoiminomethyl)hydrazono>methyl>-3-pyridinyloxy>methyl>benzoic acid sulphate 
• 136423-95-5 3-(4-methylbenzyloxy)-2-pyridinecarboxaldehyde guanylhydrazone sulphate 
• 136423-93-3 (3-benzyloxy)-2-pyridinecarboxaldehyde guanylhydrazone sulphate 

Relevant articles and documents

Improved synthesis process for lamotrigine

The invention discloses an improved synthesis process for lamotrigine. The process comprises the following steps: (1) synthesizing 2,3-dichlorobenzoyl cyanide: adding 2,3-dichlorobenzoic acid and thionyl chloride into a reactor, carrying out depressurized evaporating to remove thionyl chloride after a reaction is completed, adding cuprous cyanide into the reactor, and filtering out solids after a reaction is completed, so as to obtain a 2,3-dichlorobenzoyl cyanide solution; (2) preparing a condensate: adding aminoguanidine carbonate and an entrainer into a reactor, dropwise adding concentrated sulfuric acid, distilling off the entrainer and water, carrying out suction filtration, enabling solids to enter a reaction bottle, carrying out depressurized pumping, then, adding the 2,3-dichlorobenzoyl cyanide solution obtained in the step (1) into the reaction bottle, cooling the reaction bottle to room temperature after a reaction is completed, and carrying out suction filtration, so as to obtain the condensate; and (3) preparing cyclics: adding liquid alkali into the condensate obtained in the step (2), and carrying out crystallizing, filtering, washing and baking after a reaction, thereby obtaining the lamotrigine. According to the improved synthesis process for the lamotrigine, the quality and yield of the product, i.e., the lamotrigine can be remarkably increased, and the yield reaches 90% or more.