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CHLOROTHALONIL-4-HYDROXY, also known as Hydroxychlorothalonil, is a metabolite of Chlorothalonil (C411250). It belongs to the class of trichlorophenols, characterized by isophthalonitrile substitution at positions 2, 4, and 5 with chloro groups and a hydroxy group at position 6. As the major metabolite of chlorothalonil, CHLOROTHALONIL-4-HYDROXY plays a significant role in various applications across different industries.

28343-61-5

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28343-61-5 Usage

Uses

Used in Chemical Industry:
CHLOROTHALONIL-4-HYDROXY is used as an intermediate for the synthesis of various chemical compounds. Its unique structure with chloro and hydroxy groups makes it a valuable building block for the development of new molecules with potential applications in various fields.
Used in Pharmaceutical Industry:
CHLOROTHALONIL-4-HYDROXY is used as a starting material for the development of new pharmaceutical compounds. Its structural features can be exploited to design drugs with specific therapeutic properties, targeting various diseases and medical conditions.
Used in Agrochemical Industry:
CHLOROTHALONIL-4-HYDROXY is used as an active ingredient in the formulation of pesticides and fungicides. Its chlorinated structure provides effective control against a wide range of pests and diseases in agriculture, contributing to increased crop yield and protection.
Used in Environmental Applications:
CHLOROTHALONIL-4-HYDROXY is used in the development of environmental remediation technologies. Its ability to form complexes with various contaminants can be utilized for the removal of pollutants from soil, water, and air, thus contributing to a cleaner and healthier environment.
Used in Material Science:
CHLOROTHALONIL-4-HYDROXY is used as a component in the development of advanced materials with specific properties. Its incorporation into polymers, for instance, can enhance their stability, durability, and resistance to environmental factors, making them suitable for various applications in the material science field.

Check Digit Verification of cas no

The CAS Registry Mumber 28343-61-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,3,4 and 3 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 28343-61:
(7*2)+(6*8)+(5*3)+(4*4)+(3*3)+(2*6)+(1*1)=115
115 % 10 = 5
So 28343-61-5 is a valid CAS Registry Number.
InChI:InChI=1/C8HCl3N2O/c9-5-3(1-12)6(10)7(11)8(14)4(5)2-13/h14H

28343-61-5 Well-known Company Product Price

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  • Sigma-Aldrich

  • (88792)  2,4,5-Trichloro-6-hydroxyisophthalonitrile  analytical standard

  • 28343-61-5

  • 88792-10MG

  • 1,232.01CNY

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28343-61-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Hydroxy Chlorothalonil

1.2 Other means of identification

Product number -
Other names 2,4,5-trichloro-6-hydroxybenzene-1,3-dicarbonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:28343-61-5 SDS

28343-61-5Upstream product

28343-61-5Relevant academic research and scientific papers

Synthesis and antiinflammatory evaluation of substituted isophthalonitriles, trimesonitriles, benzonitriles, and terephthalonitriles

Heilman,Battershell,Pyne,Goble,Magee

, p. 906 - 913 (2007/10/06)

In an effort to develop nonacidic, nonsteroidal, antiinflammatory agents without gastrointestinal complications, a series of cyanobenzenes was synthesized for antiinflammatory evaluation. Twenty-seven substituted isophthalonitriles, 19 trimesonitriles, 30 benzonitriles, and 16 terephthalonitriles were tested in the rat utilizing the carrageenan-induced pedal edema assay. Based on the performance of phenylbutazone in this assay (43.8% reduction at 100 mg/kg), six compounds, dosed at 50 mg/kg, produced reductions in inflammation comparable to this standard. However, the LD50 value of each compound dosed at this level was in the range of 40-56 mg/kg in the mouse; therefore, further study was not warranted. Fifteen compounds possessed activity in excess of 20% reduction at 200 mg/kg and also possessed LD50 values greater than 300 mg/kg. Of these cyanobenzenes, trimesonitrile, 4-chlorobenzonitrile, 2-chloroterephthalonitrile, and 2-fluoroterephthalonitrile with reductions in edema of 32, 30, 46, and 49%, respectively, represent the best candidates for subsequent study.

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