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(2E)-2-[(E)-2-hydroxyethenyl]-4-oxopent-2-enedioic acid, commonly known as fumaric acid, is a dicarboxylic acid that features a conjugated system of double bonds and a carboxylic acid functional group. It is naturally found in various vegetables and fruits and plays a significant role in the human body's citric acid cycle, which is essential for energy production.

28345-81-5

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28345-81-5 Usage

Uses

Used in Food and Beverage Industry:
(2E)-2-[(E)-2-hydroxyethenyl]-4-oxopent-2-enedioic acid is used as an acidulant and flavoring agent in the food and beverage industry to provide a tangy taste and maintain the freshness of products.
Used in Pharmaceutical Production:
(2E)-2-[(E)-2-hydroxyethenyl]-4-oxopent-2-enedioic acid is used as a key component in the production of various pharmaceuticals, including those used to treat psoriasis, a skin condition characterized by red, scaly patches.
Used in Resin Production:
(2E)-2-[(E)-2-hydroxyethenyl]-4-oxopent-2-enedioic acid is used in the production of resins, which are essential for manufacturing various industrial products, such as coatings, adhesives, and composite materials.
Used in Biochemical Research:
(2E)-2-[(E)-2-hydroxyethenyl]-4-oxopent-2-enedioic acid is used in biochemical research as a substrate in the citric acid cycle, which is crucial for understanding cellular metabolism and energy production.

Check Digit Verification of cas no

The CAS Registry Mumber 28345-81-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,3,4 and 5 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 28345-81:
(7*2)+(6*8)+(5*3)+(4*4)+(3*5)+(2*8)+(1*1)=125
125 % 10 = 5
So 28345-81-5 is a valid CAS Registry Number.

28345-81-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde

1.2 Other means of identification

Product number -
Other names 4-Carboxy-2-hydroxymuconate semialdehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:28345-81-5 SDS

28345-81-5Upstream product

28345-81-5Downstream Products

28345-81-5Relevant academic research and scientific papers

Metabolism of dimethylterephthalate by Aspergillus niger

Ganji, Shobha H.,Karigar, Chandrakant S.,Pujar, Basayya G.

, p. 61 - 66 (1995)

Aspergillus niger (AG-1) metabolized dimethylterephthalate through monomethylterephthalate, terephthalate and protocatechuate. Degradation of dimethylterephthalate was followed by extraction of residual dimethylterephthalate from the spent medium. The quantitative UV analysis showed that 58 percent of the dimethylterephthalate supplement was taken up in 144 h. The metabolites were isolated from resting cell cultures. Thin layer chromatography analysis of the extract revealed the presence of two intermediates, monomethylterephthalate and terephthalate. Use of an inhibitor in resting cell culture experiment demonstrated the accumulation of protocatechuate. The time course of protocatechuate accumulation was also studied. Metabolites were identified by employing various physicochemical methods. Enzyme studies using cell-free extracts exhibited dimethylterephthalate esterase and protocatechuate dioxygenase activities. Protocatechuate was oxidized by the meta cleavage pathway. A tentative pathway for the degradation of DMTP has been proposed in A. niger.

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