28345-81-5

Basic information

• Product Name: (2E)-2-[(E)-2-hydroxyethenyl]-4-oxopent-2-enedioic acid
• CAS NO: 28345-81-5
• Molecular Formula: C₇H₆O₆
• Molecular Weight: 186.1189
• Mol File: 28345-81-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 371.2°C at 760 mmHg
• Flash Point: 192.5°C
• Density: 1.618g/cm³
• Vapor Pressure: 1.58E-06mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: (2E)-2-[(E)-2-hydroxyethenyl]-4-oxopent-2-enedioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-2-[(E)-2-hydroxyethenyl]-4-oxopent-2-enedioic acid(28345-81-5)
• EPA Substance Registry System: (2E)-2-[(E)-2-hydroxyethenyl]-4-oxopent-2-enedioic acid(28345-81-5)

Safety Data

• Hazardous Substances Data: 28345-81-5(Hazardous Substances Data)

Usage

General Description

The chemical with the IUPAC name "(2E)-2-[(E)-2-hydroxyethenyl]-4-oxopent-2-enedioic acid" is a compound that contains a conjugated system of double bonds and a carboxylic acid functional group. It is also known by the common name fumaric acid, and is found in various vegetables and fruits. Fumaric acid is also used in the food and beverage industry as an acidulant and flavoring agent, and has applications in the production of resins and pharmaceuticals. As a dicarboxylic acid, it is involved in various biological processes in the human body, including the citric acid cycle, which is an important process for energy production.

Upstream product

• 99-50-3 3,4-Dihydroxybenzoic acid 

Relevant articles and documents

Metabolism of dimethylterephthalate by Aspergillus niger

Aspergillus niger (AG-1) metabolized dimethylterephthalate through monomethylterephthalate, terephthalate and protocatechuate. Degradation of dimethylterephthalate was followed by extraction of residual dimethylterephthalate from the spent medium. The quantitative UV analysis showed that 58 percent of the dimethylterephthalate supplement was taken up in 144 h. The metabolites were isolated from resting cell cultures. Thin layer chromatography analysis of the extract revealed the presence of two intermediates, monomethylterephthalate and terephthalate. Use of an inhibitor in resting cell culture experiment demonstrated the accumulation of protocatechuate. The time course of protocatechuate accumulation was also studied. Metabolites were identified by employing various physicochemical methods. Enzyme studies using cell-free extracts exhibited dimethylterephthalate esterase and protocatechuate dioxygenase activities. Protocatechuate was oxidized by the meta cleavage pathway. A tentative pathway for the degradation of DMTP has been proposed in A. niger.