2836-03-5

Basic information

• Product Name: N,N-DIMETHYL-PHENYLENEDIAMINE
• Synonyms: N,N-DIMETHYLORTHO-PHENYLENEDIAMINE;N,N-DIMETHYL-1,2-BENZENEDIAMINE);N,N-Dimethyl-1,2-phenylenediamine;o-Aminodimethylaniline;2-Amino-N,N-dimethylaniline;(2-aminophenyl)dimethylamine(SALTDATA: FREE);N1,N1-diMethylbenzene-1,2-diaMine;N1,N1-Dimethylphenylene-1,2-diamine, N-(2-Aminophenyl)dimethylamine
• CAS NO: 2836-03-5
• Molecular Formula: C₈H₁₂N₂
• Molecular Weight: 136.19
• Mol File: 2836-03-5.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 240.49°C (rough estimate)
• Flash Point: 82.3 °C
• Appearance: /
• Density: 1.049
• Vapor Pressure: 0.0678mmHg at 25°C
• Refractive Index: 1.5914 (estimate)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 7.19±0.18(Predicted)
• CAS DataBase Reference: N,N-DIMETHYL-PHENYLENEDIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-DIMETHYL-PHENYLENEDIAMINE(2836-03-5)
• EPA Substance Registry System: N,N-DIMETHYL-PHENYLENEDIAMINE(2836-03-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 2836-03-5(Hazardous Substances Data)

Usage

General Description

N,N-Dimethyl-Phenylenediamine, also known as NDMPD or p-phenylenediamine, is an organic compound commonly used as a component in hair dyes and hair coloring products. It functions as a dye precursor, reacting with hydrogen peroxide to produce the final oxidative dye molecule, contributing to the permanent coloration of hair. NDMPD has been linked to allergic reactions and skin sensitization in some individuals, and it is considered a potential irritant and allergen. The compound is also known to be toxic to aquatic organisms and may bioaccumulate in the environment. As a result, there are regulations in place to limit its use and concentration in cosmetic products.

InChI:InChI=1/C8H12N2/c1-10(2)8-6-4-3-5-7(8)9/h3-6H,9H2,1-2H3

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 77-78-1 dimethyl sulfate 
• 88-74-4 2-nitro-aniline 
• 89291-23-6 2-(N,N-dimethylamino)phenylboronic acid 
• 1493-27-2 ortho-nitrofluorobenzene 
• 698-00-0 2-bromo-N,N-dimethylaniline 
• 874-52-2 N,N-dimethylaniline N-oxide 
• 696604-98-5 N-(2-N,N-dimethylaminophenyl)-1,1-dimethylethyl ester carbamic acid 
• 687603-39-0 N-(o-Dimethylamino-phenyl)-carbamoyl-cyanid 
• 610-17-3 N,N-dimethyl-2-nitro-benzenamine 

Downstream Products

• 100-61-8 N-methylaniline 
• 3743-22-4 2-hydroxy-N,N-dimethylaniline 
• 43035-11-6 2-amino-5-dimethylaminophenylthiosulphonic acid 

Relevant articles and documents

Two-photon "caging" groups: Effect of position isomery on the photorelease properties of aminoquinoline-derived photolabile protecting groups

High two-photon photolysis cross sections and water solubility of probes are important to avoid toxicity in biomedical applications of photolysis. Systematic variation of the position of a carboxyl electron-withdrawing group (EWG) on photolysis of 8-dimet

Tert-amino effect-promoted rearrangement of aryl isothiocyanate: A versatile approach to benzimidazothiazepines and benzimidazothioethers

A general and practical approach to benzimidazothiazepine and benzimidazothioether derivatives via an intramolecular nucleophilic addition/ring expansion rearrangement of aryl isothiocyanates promoted by the tert-amino effect has been developed. This reaction is catalyzed by low-cost camphorsulfonic acid and tolerates a broad substrate scope with complete atom economy. Structurally intriguing benzimidazothiazepine and benzimidazothioether products could be easily obtained by a simple operation in good to excellent yield (up to 98%).

Zinc Chloride Complexes with Aliphatic and Aromatic Guanidine Hybrid Ligands and Their Activity in the Ring-Opening Polymerisation of d,l-Lactide

The synthesis of the new hybrid guanidine ligands DMEGdmap, DMEGdeae, TMGdmab, DMEGdmab, TMGdeab and DMEGdeab is reported. These ligands were combined with zinc chloride, and the six obtained new complexes were structurally characterised by X-ray crystall