283608-66-2

Usage

Uses

Used in Pharmaceutical Industry:
1-(5-bromopyridin-3-yl)ethanol is used as an intermediate for the synthesis of various pharmaceutical drugs. Its unique structure allows for the creation of a wide range of compounds with different therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(5-bromopyridin-3-yl)ethanol is utilized as a building block for the development of new agrochemicals. Its structural diversity enables the design of novel compounds with improved efficacy and selectivity in agricultural applications.
Used in Chemical Research:
1-(5-bromopyridin-3-yl)ethanol serves as a valuable compound in chemical research, where it can be employed to study the effects of structural modifications on the properties and reactivity of pyridine derivatives.
Used in Drug Discovery:
Due to its potential biological activity and pharmacological properties, 1-(5-bromopyridin-3-yl)ethanol is used in drug discovery as a starting point for the development of new therapeutic agents. Its unique structural features make it an attractive candidate for the design of novel drugs with specific target interactions and improved pharmacokinetic profiles.

Upstream product

• 38940-62-4 3-acetyl-5-bromopyridine 
• 113118-81-3 5-bromopyridine-3-carbaldehyde 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 1308869-24-0 3-(2-(5-cyclohexylpyridin-3-yl)propyl)-6-o-tolylquinolin-2-amine 
• 1308870-46-3 3-(2-(5-(cyclohexenyl)pyridin-3-yl)prop-1-enyl)-6-o-tolylquinolin-2-amiE 
• 1308870-44-1 C₂₄H₂₀BrN₃ 
• 1308870-42-9 N-(4-methoxybenzyl)-3-(2-(5-bromopyridin-3-yl)prop-1-enyl)-6-o-tolylquinolin-2-amine 
• 1308870-41-8 3-(2-(5-bromopyridin-3-yl)prop-1-enyl)-2-chloro-6-o-tolylquinoline 
• 1308870-39-4 (1-(5-bromopyridin-3-yl)ethyl)triphenylphosphonium chloride 

Relevant academic research and scientific papers

FLUOROALKYL-OXADIAZOLES AND USES THEREOF

Provided herein are compounds identified as inhibitors of HDAC6 activity that can be used to treat various diseases and disorders.

Heterocycle-substituted styryl-4-phenylpyridine derivative as well as preparation method and medical application thereof

The invention relates to a heterocycle-substituted styryl-4-phenylpyridine derivative, a preparation method thereof and an application of the heterocycle-substituted styryl-4-phenylpyridine derivativeas a PD-1/PD-L1 inhibitor. Specifically, the invention discloses a compound shown as a formula (I) or pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof, and a preparation method and application thereof, and the definition of each group in the formula is shown in the specification and claims in detail.

ALDOSTERONE SYNTHASE INHIBITORS

The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2. R3, R4, R5, R6, R7, W, Y, m and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

NEW BICYCLIC DIHYDROISOQUINOLINE-1-ONE DERIVATIVES

The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4? R5, R6, A1, A2, A3, A4, A5 and n are as described herein,compositions including the compounds and methods of using the compounds as aldosterone synthase (CYP11B2 or CYP11B1) inhibitors for the treatment or prophylaxis of chronic kidney disease, congestive heart failure, hypertension, primary aldosteronism and Cushing syndrom.

NEW BICYCLIC DIHYDROISOQUINOLINE-1-ONE DERIVATIVES

The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, A1, A2, A3, A4, A5 and n are as

ALDOSTERONE SYNTHASE INHIBITORS

This invention relates to tricyclic triazole analogues of the formula I or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthetase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthetase.

AMINO HETEROARYL COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE

The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, t

BENZOXAZOLONE DERIVATIVES AS ALDOSTERONE SYMTHASE INHIBITORS

The present invention provides a compound of formula (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical comp

(3-HYDROXY-4-AMINO-BUTAN-2-YL) -3- (2-THIAZOL-2-YL-PYRROLIDINE-1-CARBONYL) BENZAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BETA-SECRETASE INHIBITORS FOR TREATING

The present invention provides novel beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer's disease. (Formula)

NOVEL ACETYL-COA CARBOXYLASE (ACC) INHIBITORS AND THEIR USE IN DIABETES, OBESITY AND METABOLIC SYNDROME

The present invention relates to compounds of formula (I) which inhibit acetyl-CoA carboxylase (ACC) and are useful for the prevention or treatment of metabolic syndrome, type II diabetes, obesity, atherosclerosis and cardiovascular diseases in humans.