2840-22-4

Usage

Uses

Used in Organic Synthesis:
DiMethylaMMoniuM 4-Methylbenzenesulfonate is used as a phase-transfer catalyst for facilitating reactions between organic and inorganic compounds. Its dual solubility in water and organic solvents enhances the reaction rates and yields, making it an essential component in the synthesis of various organic compounds.
Used in Catalytic Processes:
DiMethylaMMoniuM 4-Methylbenzenesulfonate is utilized as a catalyst in various catalytic processes due to its ability to form stable complexes with transition metals. This property allows for improved efficiency and selectivity in numerous chemical reactions, contributing to the advancement of chemical research and industrial applications.
Used in Laboratory and Industrial Settings:
Due to its relative safety and non-toxicity, DiMethylaMMoniuM 4-Methylbenzenesulfonate is an attractive choice for chemical reactions in both laboratory and industrial settings. Its use minimizes potential hazards and environmental concerns, making it a preferred reagent for a wide range of applications.

Upstream product

• 506-59-2 N,N-dimethylammonium chloride 
• 104-15-4 toluene-4-sulfonic acid 
• 124-40-3 dimethyl amine 

Downstream Products

• 400058-51-7 1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfinyl-5-(pyrazin-2-ylmethylamino)pyrazole-3-carbonitrile 
• 169046-52-0 5-(N-trifluoromethylsulfinyl)-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole 
• 120068-37-3 fipronil 
• 599-69-9 N,N,4-trimethylbenzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant academic research and scientific papers

Substrate-Controlled [5+1] Annulation of 5-Amino-1H-phenylpyrazoles with Alkenes: Divergent Synthesis of Multisubstituted 4,5-Dihydropyrazolo[1,5-a]quinazolines

A new and efficient [5+1] annulation reaction for the first synthesis of 5,5-disubstituted 4,5-dihydropyrazolo[1,5-a]quinazolines is described. This transition-metal-free tandem cyclization was performed with 5-amino-1H-phenylpyrazole and readily availabl

PROCESS FOR THE PREPARATION OF FIPRONIL AND ANALOGUES THEREOF

The present invention relates to a new and efficient process for preparing 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-IH-pyrazole-3-carbonitrile (hereinafter referred to as compound of formula I), which is useful as an intermediate for the antiparasitic agent fipronil, and a process for preparing 5-amino-3-cyano-l-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethyl sulfinylpyrazole (hereinafter referred to as compound of formula II or fipronil). In one aspect, there is provided a process for preparing fipronil comprising: a) a step of reacting CF3S(=O)ONa with the compound of formula (III) in the presence of a reducing/halogenating agent; and b) a step of oxidizing the compound of formula (I) obtained in step a) in the presence of a selective oxidizing agent, under suitable conditions, wherein the selective oxidizing agent selectively effects oxidation of (I) to the corresponding sulfoxide, Fipronil. In certain exemplary embodiments, the selective oxidizing agent is MHSO5, wherein M is an alkaline metal cation.

One-Pot synthesis of sulfonamides from primary and secondary amine derived sulfonate salts using cyanuric chloride

A convenient, mild and efficient one-pot synthesis of new sulfonamides is described. The reaction of primary or secondary amine derived sulfonate salts in the presence of cyanuric chloride, triethylamine as base, and anhydrous acetonitrile as solvent at room temperature gives the corresponding sulfonamides in good to excellent yields. Georg Thieme Verlag Stuttgart.

SUBSTITUTION OF THE ANION IN AMMONIUM AND PHOSPHONIUM CHLORIDES BY THE ACTION OF ELECTROPHILIC AGENTS

N,N-Dialkylmethaniminium iodides were obtained by the reactions of N,N-dialkylmethaniminium chlorides with methyl iodide.The reactions of ammonium and phosphonium chlorides with triethyloxonium tetrafluoroborate, dimethyl sulfate, methyl tosylate, and methyl iodide take place with substitution of the chloride ion by the BF4-, CH3SO3O-, p-CH3C6H4SO3- or I- ions.Substitution of the chloride ion of phosphonium salts by the iodide ion can be realized by the action of trimethyliodosilane.