2840-74-6

Usage

Uses

Used in Pharmaceutical Synthesis:
αα-dimethyl-δ-phenyl-n-valeric acid is utilized as a precursor in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Flavor and Fragrance Industry:
αα-dimethyl-δ-phenyl-n-valeric acid is employed as a building block in the creation of flavors and fragrances, enhancing the sensory qualities of products in these industries.
Used in Medicine:
αα-dimethyl-δ-phenyl-n-valeric acid is used for its potential biological activities, such as serving as an anti-inflammatory and analgesic agent, which can be beneficial in the treatment of pain and inflammation.
Used in Neurological Treatments:
αα-dimethyl-δ-phenyl-n-valeric acid has been studied for its potential use in the treatment of epilepsy and neurodegenerative diseases, indicating its possible role in managing these conditions.

Upstream product

• 3201-04-5 2,2-dimethyl-5-phenyl-valeric acid amide 
• 637-59-2 1-Bromo-3-phenylpropane 
• 79-31-2 isobutyric Acid 
• 71-43-2 benzene 
• 2938-48-9 3,3-dimethyl glutaric acid anhydride 
• 2938-49-0 αα-dimethyl-γ-benzoyl-n-butyric acid 

Downstream Products

• 2979-70-6 2-methyl-5-phenyl-2-pentanol 
• 33158-80-4 3,3-dimethyl-6-phenyltetrahydro-2H-pyran-2-one 
• 2979-78-4 2-<4-Methoxy-benzoyl>-2-methyl-5-phenyl-pentan 
• 2840-75-7 α,α-Dimethyl-δ-phenyl-valeriansaeure-chlorid 

Relevant academic research and scientific papers

Nickel(0)/NaHMDS adduct-mediated intramolecular alkylation of unactivated arenes via a homolytic aromatic substitution mechanism

A variety of polycycles can be synthesized via an intramolecular alkylation cyclization promoted by Ni(PPh3)4 and NaHMDS. Mechanistic investigations support the catalytic nature of Ni0 in the course of TEMPO scavenging experiments and its association with the substrate and NaHMDS to form an adduct by DOSY NMR.

Studies in the Cycloheptane Series. Part - XXXI: Friedel-Crafts Reaction of the Anhydride of αα-Dimethylglutaric Acid with Different Aromatic Hydrocarbons and Synthesis of 1,1-Dimethyl-3,4-benzo/substituted benzocycloheptanes and 1,1-Dimethylthienocycloheptane

The anhydride of αα-dimethylglutaric acid on condensation with benzene, toluene, isomeric xylenes, chlorobenzene, anisole, tetralin, naphthalene and thiophene under F.C. conditions gives the respective αα-dimethyl-γ-aroyl-n-butyric acids which on Clemmensen reduction yield δ-aryl-n-valeric acids.These on cyclisation with PPA furnish III and IV (X=O) which on Clemmensen reduction give the respective hydrocarbons (III and IV: X=H2).

Quaternary ammonium antiarrhythmic drugs

Quaternary ammonium salts of certain phenylbutylamines are useful antiarrhythmic drugs. A method for treating arrhythmia and prolonging the action potential of cardiac tissue is provided. Pharmaceutical formulations containing such quaternary ammonium salts are disclosed.