284019-58-5Relevant academic research and scientific papers
CYP2J2 and CYP2C19 are the major enzymes responsible for metabolism of albendazole and fenbendazole in human liver microsomes and recombinant P450 assay systems
Wu, Zhexue,Lee, Doohyun,Joo, Jeongmin,Shin, Jung-Hoon,Kang, Wonku,Oh, Sangtaek,Lee, Do Yup,Lee, Su-Jun,Yea, Sung Su,Lee, Hye Suk,Lee, Taeho,Liu, Kwang-Hyeon
, p. 5448 - 5456 (2013/11/06)
Albendazole and fenbendazole are broad-spectrum anthelmintics that undergo extensive metabolism to form hydroxyl and sulfoxide metabolites. Although CYP3A and flavin-containing monooxygenase have been implicated in sulfoxide metabolite formation, the enzy
