284027-37-8 Usage
General Description
6-Trifluoromethyl-1,2,3,4-tetrahydro-isoquinoline, also known by its chemical formula C10H11F3N, is a compound that belongs to the class of isoquinolines. It contains a tetrahydro-isoquinoline ring with a trifluoromethyl group attached to it. 6-TRIFLUOROMETHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE has potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its unique structure and properties. Additionally, it may also be used as a building block in organic synthesis for the creation of other related compounds. Its potential use in the pharmaceutical industry makes it a subject of interest for further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 284027-37-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,4,0,2 and 7 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 284027-37:
(8*2)+(7*8)+(6*4)+(5*0)+(4*2)+(3*7)+(2*3)+(1*7)=138
138 % 10 = 8
So 284027-37-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H10F3N/c11-10(12,13)9-2-1-8-6-14-4-3-7(8)5-9/h1-2,5,14H,3-4,6H2
284027-37-8Relevant articles and documents
Deoxofluorination of (Hetero)aromatic Acids
Alekseenko, Anatoliy N.,Bugera, Maksym Ya.,Gerus, Igor I.,Kiriakov, Oleksandr,Klipkov, Anton A.,Mykhailiuk, Pavel K.,Pustovit, Yurii,Razhyk, Bohdan,Semenov, Sergey,Starova, Viktoriia S.,Tananaiko, Oksana Yu.,Tarasenko, Karen,Tolmachev, Andrei A.,Trofymchuk, Serhii,Zaporozhets, Olga A.
, p. 3110 - 3124 (2020/03/23)
Diverse trifluoromethyl-substituted compounds were synthesized by deoxofluorination of cinnamic and (hetero)aromatic carboxylic acids with sulfur tetrafluoride. The obtained products were used as starting materials in the preparation of novel fluorinated amino acids, anilines, and aliphatic amines - valuable building blocks for medicinal chemistry and agrochemistry.
TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROISOQUINOLINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
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Page/Page column 105, (2010/02/07)
The present invention is directed to compounds of the formula I: I(wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
