284036-46-0

Upstream product

• 917-54-4 methyllithium 
• 129152-23-4 4-(3-Hydroxy-cyclohex-1-enyl)-butyric acid methyl ester 
• 73336-23-9 4-(3-oxo-cyclohex-1-enyl)-butyric acid 
• 78877-14-2 3-(4-hydroxybutyl)-2-cyclohexen-1-one 
• 129152-22-3 3-(3-Carboxypropyl)-2-cyclohexenon-methylester 

Relevant academic research and scientific papers

Amberlyst-15-catalyzed intramolecular S(N)2' oxaspirocyclization of secondary allylic alcohols. Application to the total synthesis of spirocyclic ethers theaspirane and theaspirone

A variety of substituted 1-oxaspiro[4.4]non-6-ene. 1-oxaspiro[4.5]dec-6- ene, 6-oxaspiro[4.5]dec-1-ene and 1-oxaspiro[5.5]undec-7-ene systems have been prepared by utilizing Amberlyst-15-catalyzed intramolecular S(N)2' oxaspirocyclizations of secondary allylic alcohols under mild reaction conditions in quantitative yields. This oxaspirocyclization was applied to the total synthesis of theaspirane and theaspirone from β-ionone in five steps. (C) 2000 Elsevier Science Ltd.