2844-21-5

Basic information

• Product Name: Benzenamine, N,N-dimethyl-4-[(1E)-2-(4-methylphenyl)ethenyl]-
• CAS NO: 2844-21-5
• Molecular Formula: C17H19N
• Molecular Weight: 237.345
• Mol File: 2844-21-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzenamine, N,N-dimethyl-4-[(1E)-2-(4-methylphenyl)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, N,N-dimethyl-4-[(1E)-2-(4-methylphenyl)ethenyl]-(2844-21-5)
• EPA Substance Registry System: Benzenamine, N,N-dimethyl-4-[(1E)-2-(4-methylphenyl)ethenyl]-(2844-21-5)

Safety Data

• Hazardous Substances Data: 2844-21-5(Hazardous Substances Data)

Upstream product

• 142087-16-9 1-(4-methylbenzyl)-1H-benzo[d][1,2,3]triazole 
• 94-08-6 4-methylbenzoic acid ethyl ester 
• 92146-68-4 4-(2-methoxyethenyl)-N,N-dimethylaniline 
• 380481-66-3 5,5-dimethyl-2-(4-methylphenyl)-1,3,2-dioxaborinane 
• 99-99-0 1-methyl-4-nitrobenzene 
• 2039-80-7 N,N-dimethy-4-vinylaniline 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 104-87-0 4-methyl-benzaldehyde 
• 104-82-5 4-Methylbenzyl chloride 
• 1530-37-6 (4-methylbenzyl)triphenylphosphonium chloride 
• 622-97-9 1-ethenyl-4-methylbenzene 
• 698-69-1 4-chloro-N,N-dimethylaniline 
• 204761-00-2 2-Benzotriazol-1-yl-1-(4-dimethylamino-phenyl)-2-p-tolyl-ethanone 

Relevant articles and documents

Palladium-Catalyzed Mizoroki-Heck Reaction of Nitroarenes and Styrene Derivatives

We have developed a Mizoroki-Heck reaction of nitroarenes with alkenes under palladium catalysis. The use of a Pd/BrettPhos catalyst promoted the alkenylation, whereas other catalysts led to a decrease in the product yield. In addition to nitroarenes, nitroheteroarenes were also applicable to the present reaction. The combination of a nucleophilic aromatic substitution (SNAr) with the denitrative alkenylation produced a multifunctionalized arene in a one-pot operation.

Nickel-Catalyzed system for the cross-coupling of alkenyl methyl ethers with grignard reagents under mild conditions

A nickel-catalyzed cross-coupling of alkenyl methyl ethers with Grignard reagents, under mild conditions, is described. These conditions allowed access to various stilbenes and heterocyclic stilbenic derivatives as well as to a potential anticancer agent DMU-212.

Synthesis and biological evaluation of some stilbene derivatives

Several trans and cis stilbenes with substitution n the olefinic bridge were synthesized and characterized by IR, NMR and mass spectroscopy in an effort to obtain ubstances that could be more readily formulated. All the synthesized compounds were screened against Molt4/C8, CEM and L1210 cell lines. None of these compounds were ndowed with pronounced cytostatic activity. However,Schiff derivatives emerged as cytostatic agents (IC50: 0.77-10 μg/ml) that deserve further investigation. Springer Science+Business Media, LLC 2010.