2844-82-8

Upstream product

• 1078-19-9 6-methoxy-3,4-dihydro-1(2H)-naphthalenone 
• 22117-40-4 1-Hydroxy-1-phenyl-6-methoxy-1,2,3,4-tetrahydronaphthalin 
• 2844-80-6 1,2,3,4,5,8-hexahydro-1-oxo-6-methoxynaphthalene 
• 591-51-5 phenyllithium 
• 100-58-3 phenylmagnesium bromide 
• 7664-93-9 sulfuric acid 
• 3262-89-3 triphenylboroxine 
• 108-86-1 bromobenzene 

Downstream Products

• 27331-47-1 methyl-(5-phenyl-[2]naphthyl)-ether 
• 20915-78-0 6-methoxy-1-phenyl-3,4-dihydronaphthalen-2(1H)-one 
• 19353-88-9 6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalene 
• 85035-94-5 methoxy-7, phenyl-2, dihydro-3,4 benzo (b) 5H-azepine 
• 85035-99-0 methoxy-7, phenyl-2, tetrahydro-2,3,4,5 benzo (b) 1H-azepine 
• 22117-43-7 6-Hydroxy-1-phenyltetralin 
• 78239-11-9 5,7-dibromo-6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalene 
• 78239-12-0 5-bromo-6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalene 

Relevant academic research and scientific papers

Nickel-Catalyzed Direct Synthesis of Aryl Olefins from Ketones and Organoboron Reagents under Neutral Conditions

Nickel-catalyzed addition of arylboron reagents to ketones results in aryl olefins directly. The neutral condition allows acidic protons of alcohols, phenols, and malonates to be present, and fragile structures are also tolerated.

N-SUBSTITUTED AMINOTETRALINS AS LIGANDS FOR THE NEUROPEPTIDE Y Y5 RECEPTOR USEFUL IN THE TREATMENT OF OBESITY AND OTHER DISORDERS

beta -Aminotetralin derivatives of the formula: which are ligands for the neuropeptide Y Y5 (NPY5) receptor, methods of preparation and pharmaceutical compositions containing a beta -aminotetralin derivative as the active ingredient are described. The beta -aminotetralins are useful in the treatment of disorders and diseases associated with NPY receptor subtype Y5.

N-substituted aminotetralins as ligands for the neuropeptide Y Y5 receptor useful in the treatment of obesity and other disorders

β-Aminotetralin derivatives of the formula: STR1 which are ligands for the neuropeptide Y Y5 (NPY5) receptor, methods of preparation and pharmaceutical compositions containing a β-aminotetralin derivative as the active ingredient are described. The β-aminotetralins are useful in the treatment of disorders and diseases associated with NPY receptor subtype Y5.

Hydroxy substituted phenyltetralines: compounds with affinity for estrogen and androgen receptors

Among nonsteroidal antiandrogens, mostly compounds of the Flutamide-type are described. For the development of new compounds with affinity to androgen receptors and antiandrogenic activity five new hydroxy-substituted phenyltetralines were prepared and te

Anomalous Acetoxylation of Aromatic Nuclei: Some Structural Requirements in the Substrate

For certain aromatic nuclei, bromination in acetic acid in the presence of pyridine is accompanied by nuclear acetoxylation.As first observed with galbulin, when two alkoxyl groups, one meta and one para to a benzylic centre of the substrate are present, acetoxylation occurs at the intervening ortho position.Under the given conditions, acetoxylation occurs at position 8 of 6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydronaphthalene, and at position 2 of 3,4-dimethoxy diphenyl and triphenyl-methanes.Acetoxylation does not occur in the absence of either of the alkoxy groups or in the absence of pyridine, not does it occur in the pendant ring of 1-(3',4'-dimethoxyphenyl)-1,2,3,4-tetrahydronaphthalene.These results are consistent with the earlier suggestion that the reaction occurs by way of initial oxidative formation of a doubly benzylic cation